Lothar Elling
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Explore the profile of Lothar Elling including associated specialties, affiliations and a list of published articles.
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72
Citations
690
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Recent Articles
1.
Elling L
Appl Microbiol Biotechnol
. 2025 Feb;
109(1):51.
PMID: 40014108
Leloir glycosyltransferases are instrumental in the synthesis of glycoconjugates. Nucleotide sugars as their donor substrates are still considered expensive making preparative enzymatic syntheses economically unattractive. The review highlights the development...
2.
Dey C, Sommerfeld I, Bojarova P, Kodra N, Vrbata D, Zimolova Vlachova M, et al.
Biomater Sci
. 2025 Feb;
13(6):1482-1500.
PMID: 39907577
The inherent carbohydrate-binding specificities of human galectins can serve as recognition elements in both biotechnological and biomedical applications. The combination of the carbohydrate-recognition domain (CRD) of galectins fused to peptides...
3.
Frohnmeyer H, Kodra N, Elling L
J Biotechnol
. 2024 Sep;
395:1-11.
PMID: 39241966
Enzymatic production of nucleotide sugars on a multigram scale presents a challenge, as only a few processes have been reported for large-scale nucleotide sugar production. They rely primarily on batch...
4.
Sommerfeld I, Dalken E, Elling L, Pich A
Macromol Biosci
. 2024 Jul;
24(9):e2400075.
PMID: 39018489
Enzymes play a vital role in synthesizing complex biological molecules like hyaluronic acid (HA). Immobilizing enzymes on support materials is essential for their efficient use and reuse in multiple cycles....
5.
Sommerfeld I, Palm P, Hussnaetter K, Pieper M, Bulut S, Lile T, et al.
Biomacromolecules
. 2024 May;
25(6):3807-3822.
PMID: 38807305
Glycans, composed of linked monosaccharides, play crucial roles in biology and find diverse applications. Enhancing their enzymatic synthesis can be achieved by immobilizing enzymes on materials such as microgels. Here,...
6.
Frohnmeyer H, Verkade J, Spiertz M, Rentsch A, Hoffmann N, Sobota M, et al.
ChemSusChem
. 2024 Apr;
17(19):e202400311.
PMID: 38655621
Azido sugars hold great promise as substrates in numerous click-chemistry applications. However, the synthesis of activated azido sugars is limited by cost and complexity. Conventional chemical activation methods are intricate...
7.
Singh B, Tabatabaei M, Pandit A, Elling L, Gupta V
Biotechnol Adv
. 2024 Feb;
72:108324.
PMID: 38360155
No abstract available.
8.
Hussnaetter K, Palm P, Pich A, Franzreb M, Rapp E, Elling L
Biotechnol Adv
. 2023 Jul;
67:108208.
PMID: 37437855
Glycans are the most abundant biopolymers on earth and are constituents of glycoproteins, glycolipids, and proteoglycans with multiple biological functions. The availability of different complex glycan structures is of major...
9.
Behren S, Yu J, Pett C, Schorlemer M, Heine V, Fischoder T, et al.
Angew Chem Int Ed Engl
. 2023 Apr;
62(32):e202302437.
PMID: 37067376
Mucin glycoproteins are essential components of the mucosal barrier, which protects the host from pathogens. Throughout evolution, bacteria have developed strategies to modulate and penetrate this barrier, and cause virulence...
10.
Dey C, Palm P, Elling L
Molecules
. 2023 Feb;
28(3).
PMID: 36770718
Galectins are β-galactosyl-binding proteins that fulfill essential physiological functions. In the biotechnological field, galectins are versatile tools, such as in the development of biomaterial coatings or the early-stage diagnosis of...