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Lorri R Marek

Explore the profile of Lorri R Marek including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 567
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Recent Articles
1.
Marek L, Kagan J
Immunity . 2012 Apr; 36(4):612-22. PMID: 22464168
The cell biological principles that govern innate immune responses in Drosophila are unknown. Here, we report that Toll signaling in flies was dictated by the subcellular localization of the adaptor...
2.
Zanoni I, Ostuni R, Marek L, Barresi S, Barbalat R, Barton G, et al.
Cell . 2011 Nov; 147(4):868-80. PMID: 22078883
The transport of Toll-like Receptors (TLRs) to various organelles has emerged as an essential means by which innate immunity is regulated. While most of our knowledge is restricted to regulators...
3.
Marek L, Kagan J
Front Biosci (Landmark Ed) . 2011 May; 16(6):2060-8. PMID: 21622162
While initial studies of Toll-like Receptor (TLR) signaling mainly focused on genetic analysis of signal transduction, recent work has highlighted the importance of understanding the basic cell biology underlying receptor...
4.
Marek L, Kottemann M, Glazer P, Bale A
DNA Repair (Amst) . 2008 Feb; 7(3):476-86. PMID: 18258493
Cells mutant for multiple endocrine neoplasia type I (MEN1) or any of the Fanconi anemia (FA) genes are hypersensitive to the killing effects of crosslinking agents, but the precise roles...
5.
Marek L, Bale A
DNA Repair (Amst) . 2006 Jul; 5(11):1317-26. PMID: 16860002
Fanconi anemia (FA) is a genetically heterogeneous disease characterized by developmental defects, progressive bone marrow failure and cancer susceptibility. Cells derived from patients with FA show spontaneous chromosomal aberrations and...
6.
Busygina V, Suphapeetiporn K, Marek L, Stowers R, Xu T, Bale A
Hum Mol Genet . 2004 Aug; 13(20):2399-408. PMID: 15333582
Multiple endocrine neoplasia type I (MEN1) is an autosomal dominant cancer predisposition syndrome, the gene for which encodes a nuclear protein, menin. The biochemical function of this protein has not...