Lori R Roust
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Explore the profile of Lori R Roust including associated specialties, affiliations and a list of published articles.
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23
Citations
272
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Recent Articles
1.
Winslow W, Judd J, Tallino S, Roust L, Filippis E, Brown B, et al.
bioRxiv
. 2025 Mar;
PMID: 40060610
Highlights: Obesity is linked to increased insulin resistance (IR) and systemic inflammation, both of which are recognized risk factors for Alzheimer's disease (AD).Women exhibit lower circulating choline levels compared to...
2.
Katsanos C, Tran L, Hoffman N, Roust L, Filippis E, Mandarino L, et al.
J Clin Endocrinol Metab
. 2024 Oct;
PMID: 39401337
Context: Humans with obesity and insulin resistance exhibit lipid accumulation in skeletal muscle, but the underlying biological mechanisms responsible for the accumulation of lipid in the muscle of these individuals...
3.
Katsanos C, Tran L, Hoffman N, Roust L, Filippis E, Mandarino L, et al.
bioRxiv
. 2024 Jun;
PMID: 38915696
Context: Humans with obesity and insulin resistance exhibit lipid accumulation in skeletal muscle, but the underlying biological mechanisms responsible for the accumulation of lipid in the muscle of these individuals...
4.
Freitas E, Kras K, Roust L, De Filippis E, Kimball S, Buras M, et al.
Obesity (Silver Spring)
. 2023 Oct;
31(11):2689-2698.
PMID: 37840435
Objective: This study tested the hypothesis that expression of insulin-like growth factor 1 (IGF-1) protein and mRNA splice variants is lower in skeletal muscle of humans with obesity who have...
5.
Ravichandran J, Roust L, Katsanos C
Front Physiol
. 2022 Apr;
13:858341.
PMID: 35444566
Obesity negatively impacts skeletal muscle protein metabolism, and also impairs skeletal muscle maintenance and regeneration. We analyzed muscle biopsy samples from humans with increased body mass index (BMI) (i.e. >...
6.
Garcia L, Zapata-Bustos R, Day S, Campos B, Hamzaoui Y, Wu L, et al.
Metabolites
. 2022 Mar;
12(3).
PMID: 35323665
Skeletal muscle is highly plastic and dynamically regulated by the body's physical demands. This study aimed to determine the plasticity of skeletal muscle DNA methylation in response to 8 weeks...
7.
Garcia L, Day S, Coletta R, Campos B, Benjamin T, Filippis E, et al.
Clin Epigenetics
. 2021 May;
13(1):100.
PMID: 33933146
Background: The mechanisms of weight loss and metabolic improvements following bariatric surgery in skeletal muscle are not well known; however, epigenetic modifications are likely to contribute. The aim of our...
8.
Wahwah N, Kras K, Roust L, Katsanos C
Am J Physiol Endocrinol Metab
. 2020 Jan;
318(4):E538-E553.
PMID: 31990577
Mitochondria from skeletal muscle of humans with obesity often display alterations with respect to their morphology, proteome, biogenesis, and function. These changes in muscle mitochondria are considered to contribute to...
9.
Kras K, Hoffman N, Roust L, Benjamin T, De Filippis E, Katsanos C
Med Sci Sports Exerc
. 2018 Oct;
51(3):445-453.
PMID: 30363008
Introduction: Current evidence indicates mitochondrial dysfunction in humans with obesity. Acute exercise appears to enhance mitochondrial function in the muscle of nonobese humans, but its effects on mitochondrial function in...
10.
Kras K, Langlais P, Hoffman N, Roust L, Benjamin T, De Filippis E, et al.
Metabolism
. 2018 Sep;
89:18-26.
PMID: 30253140
Background: Skeletal muscle mitochondrial content and function appear to be altered in obesity. Mitochondria in muscle are found in well-defined regions within cells, and they are arranged in a way...