Lorenzo L Pesce
Overview
Explore the profile of Lorenzo L Pesce including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
42
Citations
746
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Lennon N, Kottyan L, Kachulis C, Abul-Husn N, Arias J, Belbin G, et al.
Nat Med
. 2024 Feb;
30(2):480-487.
PMID: 38374346
Polygenic risk scores (PRSs) have improved in predictive performance, but several challenges remain to be addressed before PRSs can be implemented in the clinic, including reduced predictive performance of PRSs...
2.
Puckelwartz M, Pesce L, Hernandez E, Webster G, Dellefave-Castillo L, Russell M, et al.
Genome Med
. 2024 Jan;
16(1):13.
PMID: 38229148
Background: Sudden unexpected death in children is a tragic event. Understanding the genetics of sudden death in the young (SDY) enables family counseling and cascade screening. The objective of this...
3.
Lennon N, Kottyan L, Kachulis C, Abul-Husn N, Arias J, Belbin G, et al.
medRxiv
. 2023 Jun;
PMID: 37333246
Polygenic risk scores (PRS) have improved in predictive performance supporting their use in clinical practice. Reduced predictive performance of PRS in diverse populations can exacerbate existing health disparities. The NHGRI-funded...
4.
Puckelwartz M, Pesce L, Hernandez E, Webster G, Dellefave-Castillo L, Russell M, et al.
medRxiv
. 2023 Apr;
PMID: 37034657
Background: Sudden unexpected death in children is a tragic event. Understanding the genetics of sudden death in the young (SDY) enables family counseling and cascade screening. The objective of this...
5.
Fischer J, Monroe T, Pesce L, Sawicki K, Quattrocelli M, Bauer R, et al.
Hum Mol Genet
. 2022 Jul;
32(1):15-29.
PMID: 35904451
Genetic variation in genes regulating metabolism may be advantageous in some settings but not others. The non-failing adult heart relies heavily on fatty acids as a fuel substrate and source...
6.
Pickens C, Gao C, Cuttica M, Smith S, Pesce L, Grant R, et al.
Am J Respir Crit Care Med
. 2021 Aug;
204(8):921-932.
PMID: 34409924
Current guidelines recommend patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia receive empirical antibiotics for suspected bacterial superinfection on the basis of weak evidence. Rates of ventilator-associated pneumonia...
7.
Webster G, Puckelwartz M, Pesce L, Dellefave-Castillo L, Vanoye C, Potet F, et al.
JAMA Cardiol
. 2021 Aug;
6(11):1247-1256.
PMID: 34379075
Importance: Postmortem genetic testing of young individuals with sudden death has previously identified pathogenic gene variants. However, prior studies primarily considered highly penetrant monogenic variants, often without detailed decedent and...
8.
Puckelwartz M, Pesce L, Dellefave-Castillo L, Wheeler M, Pottinger T, Robinson A, et al.
J Am Heart Assoc
. 2021 Mar;
10(7):e019944.
PMID: 33764162
Background Inherited cardiomyopathies display variable penetrance and expression, and a component of phenotypic variation is genetically determined. To evaluate the genetic contribution to this variable expression, we compared protein coding...
9.
Manerikar A, Querrey M, Cerier E, Kim S, Odell D, Pesce L, et al.
J Surg Res
. 2020 Dec;
263:274-284.
PMID: 33309173
Background: The magnitude of association and quality of evidence comparing surgical approaches for lung cancer resection has not been analyzed. This has resulted in conflicting information regarding the relative superiority...
10.
Pottinger T, Puckelwartz M, Pesce L, Robinson A, Kearns S, Pacheco J, et al.
J Am Heart Assoc
. 2020 Feb;
9(3):e013808.
PMID: 32009526
Background Genome sequencing coupled with electronic heath record data can uncover medically important genetic variation. Interpretation of rare genetic variation and its role in mediating cardiovascular phenotypes is confounded by...