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Lorena Aguilar-Arnal

Explore the profile of Lorena Aguilar-Arnal including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 487
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Recent Articles
1.
Rivera-Alvarez I, Vazquez-Lizarraga R, Mendoza-Viveros L, Sotelo-Rivera I, Viveros-Ruiz T, Morales-Maza J, et al.
Commun Biol . 2025 Mar; 8(1):398. PMID: 40057615
The prevalence of type 2 diabetes (T2D) has increased significantly over the past three decades, with an estimated 30-40% of cases remaining undiagnosed. Brown and beige adipose tissues are known...
2.
Liu P, Nadeef S, Serag M, Paytuvi-Gallart A, Abadi M, Valle F, et al.
EMBO J . 2024 Oct; 43(23):6052-6075. PMID: 39433902
Circadian rhythmicity of gene expression is a conserved feature of cell physiology. This involves fine-tuning between transcriptional and post-transcriptional mechanisms and strongly depends on the metabolic state of the cell....
3.
Pacheco-Bernal I, Becerril-Perez F, Bustamante-Zepeda M, Gonzalez-Suarez M, Olmedo-Suarez M, Hernandez-Barrientos L, et al.
Cell Mol Life Sci . 2024 Jul; 81(1):309. PMID: 39060446
The circadian clock system coordinates metabolic, physiological, and behavioral functions across a 24-h cycle, crucial for adapting to environmental changes. Disruptions in circadian rhythms contribute to major metabolic pathologies like...
4.
Gonzalez-Suarez M, Aguilar-Arnal L
Front Genet . 2024 May; 15:1343030. PMID: 38818037
Circadian rhythms, essential 24-hour cycles guiding biological functions, synchronize organisms with daily environmental changes. These rhythms, which are evolutionarily conserved, govern key processes like feeding, sleep, metabolism, body temperature, and...
5.
Ahmed A, Syed J, Chi L, Wang Y, Perez-Romero C, Lee D, et al.
Nat Cardiovasc Res . 2024 Apr; 2(2):174-191. PMID: 38665902
Cardiac metabolism is deranged in heart failure, but underlying mechanisms remain unclear. Here, we show that lysine demethylase 8 (Kdm8) maintains an active mitochondrial gene network by repressing , thus...
6.
Sanchez-Ramirez E, Ung T, Stringari C, Aguilar-Arnal L
Mol Neurobiol . 2024 Feb; 61(9):6688-6707. PMID: 38340204
Stem cells possess extraordinary capacities for self-renewal and differentiation, making them highly valuable in regenerative medicine. Among these, neural stem cells (NSCs) play a fundamental role in neural development and...
7.
Escalante-Covarrubias Q, Mendoza-Viveros L, Gonzalez-Suarez M, Sitten-Olea R, Velazquez-Villegas L, Becerril-Perez F, et al.
Nat Commun . 2023 Mar; 14(1):1685. PMID: 36973248
The circadian clock is an endogenous time-tracking system that anticipates daily environmental changes. Misalignment of the clock can cause obesity, which is accompanied by reduced levels of the clock-controlled, rhythmic...
8.
Mendoza-Viveros L, Marmolejo-Gutierrez C, Cid-Castro C, Escalante-Covarrubias Q, Montellier E, Carreno-Vazquez E, et al.
Glia . 2023 Mar; 71(7):1626-1647. PMID: 36919670
Hypothalamic circuits compute systemic information to control metabolism. Astrocytes residing within the hypothalamus directly sense nutrients and hormones, integrating metabolic information, and modulating neuronal responses. Nevertheless, the role of the...
9.
Nunez-Olvera S, Aguilar-Arnal L, Cisneros-Villanueva M, Hidalgo-Miranda A, Marchat L, Salinas-Vera Y, et al.
Cells . 2022 Nov; 11(21). PMID: 36359853
Organotypic three-dimensional (3D) cell cultures more accurately mimic the characteristics of solid tumors in vivo in comparison with traditional two-dimensional (2D) monolayer cell models. Currently, studies on the regulation of...
10.
Sanchez-Ramirez E, Ung T, Alarcon Del Carmen A, Del Toro-Rios X, Fajardo-Orduna G, Noriega L, et al.
J Cell Biol . 2022 Oct; 221(12). PMID: 36197339
Adipocytes are the main cell type in adipose tissue, which is a critical regulator of metabolism, highly specialized in storing energy as fat. Adipocytes differentiate from multipotent mesenchymal stromal cells...