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Lorcan P McGarvey

Explore the profile of Lorcan P McGarvey including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 943
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Recent Articles
1.
Ghosh S, Alkawadri T, McGarvey L, Hollywood M, Thornbury K, Sergeant G
Am J Physiol Lung Cell Mol Physiol . 2025 Jan; 328(2):L301-L312. PMID: 39772966
Cholinergic tone is elevated in obstructive lung conditions such as chronic obstructive pulmonary disease (COPD) and asthma, but the cellular mechanisms underlying cholinergic contractions of airway smooth muscle (ASM) are...
2.
Murphy M, Hunt D, Herron M, McDonnell J, Alshuhoumi R, McGarvey L, et al.
J Immunol . 2024 May; 213(1):75-85. PMID: 38758115
In chronic obstructive pulmonary disease (COPD), inflammation gives rise to protease-mediated degradation of the key extracellular matrix protein, elastin, which causes irreversible loss of pulmonary function. Intervention against proteolysis has...
3.
Dunne O, Martin S, Sergeant G, McAuley D, OKane C, Button B, et al.
Respir Res . 2024 Apr; 25(1):188. PMID: 38678280
Repetitive bouts of coughing expose the large airways to significant cycles of shear stress. This leads to the release of alarmins and the tussive agent adenosine triphosphate (ATP) which may...
4.
Parker S, Smith J, Birring S, Chamberlain-Mitchell S, Gruffydd-Jones K, Haines J, et al.
Thorax . 2023 Dec; 78(Suppl 6):s3-s19. PMID: 38088193
No abstract available.
5.
Song W, Dupont L, Birring S, Chung K, Dabrowska M, Dicpinigaitis P, et al.
ERJ Open Res . 2023 Nov; 9(6). PMID: 38020564
Background: Current guidelines on the management of chronic cough do not provide recommendations for the operation of specialist cough clinics. The objective of the present study was to develop expert...
6.
McGarvey L, Harper G, Silvey M, Langerman H
Curr Med Res Opin . 2023 Nov; 39(12):1717-1728. PMID: 37994434
Objective: Treatment options for adults with chronic cough (CC) are limited. This study reports on the health status and experiences of patients with recent healthcare evaluation for CC. Methods: This...
7.
Matthews R, Bradley E, Hollywood M, Lundy F, McGarvey L, Sergeant G, et al.
Am J Physiol Cell Physiol . 2023 Nov; 326(1):C1-C9. PMID: 37955124
Airway smooth muscle (ASM) cells from mouse bronchus express a fast sodium current mediated by Na1.7. We present evidence that this current is regulated by cAMP. ASM cells were isolated...
8.
Drake M, McGarvey L, Morice A
Clin Transl Med . 2023 Jul; 13(8):e1343. PMID: 37501282
Background: Chronic cough is a burdensome condition characterized by persistent cough lasting longer than 8 weeks. Chronic cough can significantly affect quality of life, physical function and productivity, with many...
9.
Birring S, Morice A, Dicpinigaitis P, McGarvey L, Pavord I, Green S, et al.
Am J Respir Crit Care Med . 2023 Apr; 207(12):1650-1651. PMID: 37104844
No abstract available.
10.
Birring S, Dicpinigaitis P, Smith J, Morice A, McGarvey L, Pavord I, et al.
Am J Respir Crit Care Med . 2023 Mar; 207(11):1539-1542. PMID: 36996347
No abstract available.