Lora V Hooper
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Explore the profile of Lora V Hooper including associated specialties, affiliations and a list of published articles.
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99
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16954
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Recent Articles
1.
Pena-Lopez Y, Tareen N, Zhang B, Raman I, Arana C, Zhu C, et al.
Pediatr Rheumatol Online J
. 2025 Jan;
23(1):9.
PMID: 39849638
Background: An accurate diagnosis of septic versus reactive or autoimmune arthritis remains clinically challenging. A multi-omics strategy comprising metagenomic and proteomic technologies were undertaken for children diagnosed with presumed septic...
2.
Li Y, Bel S, Benjamin J, Ruhn K, Hassell B, Behrendt C, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(49):e2410205121.
PMID: 39602254
Autophagy is a key innate immune defense mechanism in intestinal epithelial cells. Bacterial invasion of epithelial cells activates antibacterial autophagy through a process that requires the innate immune adaptor protein...
3.
Rodrigues M, Sabaeifard P, Yildiz M, Lyon A, Coughlin L, Ahmed S, et al.
Cell Host Microbe
. 2024 Feb;
32(3):396-410.e6.
PMID: 38359828
Antibiotic resistance and evasion are incompletely understood and complicated by the fact that murine interval dosing models do not fully recapitulate antibiotic pharmacokinetics in humans. To better understand how gastrointestinal...
4.
Zarek C, Dende C, Coronado J, Pendse M, Dryden P, Hooper L, et al.
PLoS Pathog
. 2023 Oct;
19(10):e1011691.
PMID: 37847677
Even though gammaherpesvirus and parasitic infections are endemic in parts of the world, there is a lack of understanding about the outcome of coinfection. In humans, coinfections usually occur sequentially,...
5.
Wang Y, Wang M, Chen J, Li Y, Kuang Z, Dende C, et al.
Science
. 2023 Aug;
381(6660):851-857.
PMID: 37616368
The intestinal microbiota regulates mammalian lipid absorption, metabolism, and storage. We report that the microbiota reprograms intestinal lipid metabolism in mice by repressing the expression of long noncoding RNA (lncRNA)...
6.
Singh A, Kumar R, Yin J, Brooks Ii J, Kathania M, Mukherjee S, et al.
Nat Commun
. 2023 Aug;
14(1):4972.
PMID: 37591835
Th17 cells that produce Interleukin IL-17 are pathogenic in many human diseases, including inflammatory bowel disease, but are, paradoxically, essential for maintaining the integrity of the intestinal barrier in a...
7.
Pendse M, De Selle H, Vo N, Quinn G, Dende C, Li Y, et al.
Elife
. 2023 May;
12.
PMID: 37159507
Peristaltic movement of the intestine propels food down the length of the gastrointestinal tract to promote nutrient absorption. Interactions between intestinal macrophages and the enteric nervous system regulate gastrointestinal motility,...
8.
Choi Y, Lichterman J, Coughlin L, Poulides N, Li W, Del Valle P, et al.
Sci Immunol
. 2023 Mar;
8(81):eabo2003.
PMID: 36867675
Gut microbiota, specifically gut bacteria, are critical for effective immune checkpoint blockade therapy (ICT) for cancer. The mechanisms by which gut microbiota augment extraintestinal anticancer immune responses, however, are largely...
9.
Rodrigues M, Sabaeifard P, Yildiz M, Coughlin L, Ahmed S, Behrendt C, et al.
bioRxiv
. 2023 Jan;
PMID: 36711614
systems have provided great insight into the mechanisms of antibiotic resistance. Yet, approaches cannot reflect the full complexity of what transpires within a host. As the mammalian gut is host...
10.
Ceglia S, Berthelette A, Howley K, Li Y, Mortzfeld B, Bhattarai S, et al.
Nat Immunol
. 2023 Jan;
24(3):531-544.
PMID: 36658240
Immunoglobulin A (IgA) secretion by plasma cells, terminally differentiated B cells residing in the intestinal lamina propria, assures microbiome homeostasis and protects the host against enteric infections. Exposure to diet-derived...