Cassie L Behrendt
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Explore the profile of Cassie L Behrendt including associated specialties, affiliations and a list of published articles.
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20
Citations
2581
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Recent Articles
1.
Li Y, Bel S, Benjamin J, Ruhn K, Hassell B, Behrendt C, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(49):e2410205121.
PMID: 39602254
Autophagy is a key innate immune defense mechanism in intestinal epithelial cells. Bacterial invasion of epithelial cells activates antibacterial autophagy through a process that requires the innate immune adaptor protein...
2.
Wang Y, Wang M, Chen J, Li Y, Kuang Z, Dende C, et al.
Science
. 2023 Aug;
381(6660):851-857.
PMID: 37616368
The intestinal microbiota regulates mammalian lipid absorption, metabolism, and storage. We report that the microbiota reprograms intestinal lipid metabolism in mice by repressing the expression of long noncoding RNA (lncRNA)...
3.
Hu Z, Zhang C, Sifuentes-Dominguez L, Zarek C, Propheter D, Kuang Z, et al.
Science
. 2021 Nov;
374(6568):eabe6723.
PMID: 34735226
A diverse group of antimicrobial proteins (AMPs) helps protect the mammalian intestine from varied microbial challenges. We show that small proline-rich protein 2A (SPRR2A) is an intestinal antibacterial protein that...
4.
Brooks 2nd J, Behrendt C, Ruhn K, Lee S, Raj P, Takahashi J, et al.
Cell
. 2021 Jul;
184(16):4154-4167.e12.
PMID: 34324837
Environmental light cycles entrain circadian feeding behaviors in animals that produce rhythms in exposure to foodborne bacteria. Here, we show that the intestinal microbiota generates diurnal rhythms in innate immunity...
5.
Zhu W, Winter M, Spiga L, Hughes E, Chanin R, Mulgaonkar A, et al.
Cell Host Microbe
. 2020 Feb;
27(3):376-388.e8.
PMID: 32075741
During short-lived perturbations, such as inflammation, the gut microbiota exhibits resilience and reverts to its original configuration. Although microbial access to the micronutrient iron is decreased during colitis, pathogens can...
6.
Kuang Z, Wang Y, Li Y, Ye C, Ruhn K, Behrendt C, et al.
Science
. 2019 Oct;
365(6460):1428-1434.
PMID: 31604271
Circadian rhythmicity is a defining feature of mammalian metabolism that synchronizes metabolic processes to day-night light cycles. Here, we show that the intestinal microbiota programs diurnal metabolic rhythms in the...
7.
Gillis C, Hughes E, Spiga L, Winter M, Zhu W, Carvalho T, et al.
Cell Host Microbe
. 2018 Apr;
23(4):570.
PMID: 29649446
No abstract available.
8.
Zhu W, Winter M, Byndloss M, Spiga L, Duerkop B, Hughes E, et al.
Nature
. 2018 Jan;
553(7687):208-211.
PMID: 29323293
Inflammatory diseases of the gastrointestinal tract are frequently associated with dysbiosis, characterized by changes in gut microbial communities that include an expansion of facultative anaerobic bacteria of the Enterobacteriaceae family...
9.
Gillis C, Hughes E, Spiga L, Winter M, Zhu W, Carvalho T, et al.
Cell Host Microbe
. 2017 Dec;
23(1):54-64.e6.
PMID: 29276172
During Salmonella-induced gastroenteritis, mucosal inflammation creates a niche that favors the expansion of the pathogen population over the microbiota. Here, we show that Salmonella Typhimurium infection was accompanied by dysbiosis,...
10.
Spiga L, Winter M, Carvalho T, Zhu W, Hughes E, Gillis C, et al.
Cell Host Microbe
. 2017 Aug;
22(3):291-301.e6.
PMID: 28844888
The mucosal inflammatory response induced by Salmonella serovar Typhimurium creates a favorable niche for this gut pathogen. Conventional wisdom holds that S. Typhimurium undergoes an incomplete tricarboxylic acid (TCA) cycle...