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Lora Talley Watts

Explore the profile of Lora Talley Watts including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 812
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Recent Articles
11.
Li W, Long J, Watts L, Jiang Z, Shen Q, Li Y, et al.
PLoS One . 2014 Dec; 9(12):e114173. PMID: 25478693
Blood-brain barrier (BBB) disruption is common following traumatic brain injury (TBI). Dynamic contrast enhanced (DCE) MRI can longitudinally measure the transport coefficient Ktrans which reflects BBB permeability. Ktrans measurements however...
12.
Long J, Watts L, Chemello J, Huang S, Shen Q, Duong T
J Neurotrauma . 2014 Sep; 32(8):598-607. PMID: 25203249
This study reports T2 and diffusion-tensor magnetic resonance imaging (MRI) studies of a mild open-skull, controlled cortical impact injury in rats (n=6) from 3 h to up to 14 d...
13.
Watts L, Lloyd R, Garling R, Duong T
Brain Sci . 2014 Jun; 3(2):540-60. PMID: 24961414
Stroke is the fourth leading cause of death and the leading cause of long-term disability in the United States. Blood flow deficit results in an expanding infarct core with a...
14.
Muir E, Watts L, Tiwari Y, Bresnen A, Shen Q, Duong T
Methods Mol Biol . 2014 Feb; 1135:205-11. PMID: 24510866
Magnetic resonance imaging can be utilized as a quantitative and noninvasive method to image cerebral blood flow. The two most common techniques used to detect cerebral blood flow are dynamic...
15.
Watts L, Long J, Chemello J, Van Koughnet S, Fernandez A, Huang S, et al.
J Neurotrauma . 2014 Feb; 31(11):1063-71. PMID: 24479842
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Methylene blue (MB) has known energy-enhancing and antioxidant properties. This study tested the hypothesis that MB treatment...
16.
Shen Q, Du F, Huang S, Rodriguez P, Watts L, Duong T
PLoS One . 2013 Nov; 8(11):e79833. PMID: 24278191
Methylene blue (MB) has unique energy-enhancing and antioxidant properties and is FDA-approved drug to treat methemoglobinemia and cyanide poisoning. This study evaluated the efficacy of MB to treat ischemic stroke...
17.
Fletcher L, Evans T, Watts L, Jimenez D, Digicaylioglu M
PLoS One . 2013 Jul; 8(7):e68281. PMID: 23861877
Ischemic stroke is the leading cause of serious, long-term adult disability and is associated with sensorimotor and cognitive impairments due to neuronal degeneration. Currently, recombinant tissue plasminogen activator (rTPA) is...
18.
Sun Y, Liu Y, Watts L, Sun Q, Zhong Z, Yang G, et al.
PLoS One . 2013 Jul; 8(6):e67402. PMID: 23826288
Background: A number of studies have reported an association of angiotensin-converting enzyme (ACE) gene polymorphism with primary intracerebral hemorrhage (PICH), however the reports have demonstrated inconclusive results. To clarify this...
19.
Zheng W, Watts L, Holstein D, Wewer J, Lechleiter J
J Cereb Blood Flow Metab . 2013 Jan; 33(4):600-11. PMID: 23321785
Glia-based neuroprotection strategies are emerging as promising new avenues to treat brain damage. We previously reported that activation of the glial-specific purinergic receptor, P2Y(1)R, reduces both astrocyte swelling and brain...
20.
Watts L, Sprague S, Zheng W, Garling R, Jimenez D, Digicaylioglu M, et al.
J Neurotrauma . 2012 Oct; 30(1):55-66. PMID: 23046422
Traumatic brain injury (TBI) is the leading cause of death and disability in children and young adults. Neuroprotective agents that may promote repair or counteract damage after injury do not...