Long-Fei Mao
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Explore the profile of Long-Fei Mao including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
79
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Recent Articles
1.
Synthesis and Activity Study of Gefitinib Derivatives Inducing Mitochondrial Apoptosis in Hela Cells
Li Y, Hou X, Liu S, Chen Z, Wu Q, He B, et al.
Chem Biol Drug Des
. 2024 Dec;
104(6):e70035.
PMID: 39715290
Cervical cancer is the fourth most common cancer among women globally. Its development is closely linked to accelerated cell cycle progression and the inhibition of apoptosis in cervical cancer tissues....
2.
Zhang L, Wang M, Li T, He Y, Li S, Wang L, et al.
J Food Sci
. 2024 Aug;
89(9):5748-5762.
PMID: 39150691
A novel and facile surface molecularly imprinted polymer coated on magnetic chitosan (FeO@CS@MIP) was fabricated for the selective recognition and enrichment of naringin (NRG). The FeO@CS@MIP was prepared based on...
3.
Gao E, Wang Y, Fan G, Xu G, Wu Z, Liu Z, et al.
Sci Rep
. 2024 Apr;
14(1):9223.
PMID: 38649732
A series of 20 novel gefitinib derivatives incorporating the 1,2,3-triazole moiety were designed and synthesized. The synthesized compounds were evaluated for their potential anticancer activity against EGFR wild-type human non-small...
4.
Hou X, Mao L, Guo Y, Lou C, Wang L, Li R, et al.
Front Pharmacol
. 2023 Aug;
14:1238587.
PMID: 37608893
Based on the modification of the structure of dolutegravir, we introduced 1,2,3-triazole moieties with different substituted groups and obtained a lot of novel dolutegravir derivatives. The activity of A549 cells...
5.
Hou X, Wu Z, Zhan A, Gao E, Mao L, Wang H, et al.
Front Chem
. 2023 Jul;
11:1222825.
PMID: 37408559
Indoleamine 2,3-dioxygenase 1 (IDO1) has attracted much attention in the field of cancer immunotherapy as an immunomodulatory enzyme. To identify potential IDO1 inhibitors, a novel series of compounds with N,N-diphenylurea...
6.
Chen X, Mao L, Tian S, Tian X, Meng X, Wang M, et al.
Front Pharmacol
. 2022 Dec;
13:1028692.
PMID: 36467103
Previous report showed that a variety of icotinib derivatives bearing different 1,2,3-triazole moieties, which could be readily prepared copper (I)-catalyzed cycloaddition (CuAAC) reaction between icotinib and different azides, exhibited interesting...
7.
Sun S, Deng P, Peng C, Ji H, Mao L, Peng L
Cancer Manag Res
. 2022 Dec;
14:3335-3345.
PMID: 36465707
Introduction: Chitosan is the product of the natural polysaccharide chitin removing part of the acetyl group, and exhibits various physiological and bioactive functions. Selenium modification has been proved to further...
8.
Hou X, Gong X, Mao L, Sun G, Yang J
Front Pharmacol
. 2022 Aug;
13:940704.
PMID: 36034879
Erlotinib is a highly specific and reversible epidermal growth factor receptor tyrosine kinase inhibitor for the targeted therapy of non-small-cell lung cancer (NSCLC) However, the efficacy of erlotinib is limited...
9.
Sun S, Deng P, Peng C, Ji H, Mao L, Peng L
Polymers (Basel)
. 2022 Jul;
14(14).
PMID: 35890675
The ethanol precipitation method has been widely-used for polysaccharides preparation. However, the alcohol-soluble fractions have always been ignored, which causes significant wastes of resources and energies. In this study, the...
10.
Xu G, Gong X, Zhu Y, Yao X, Peng L, Sun G, et al.
Front Pharmacol
. 2022 Jun;
13:854965.
PMID: 35677437
Indoleamine 2,3-dioxygenase 1 (IDO1) plays a predominant role in cancer immunotherapy which catalyzes the initial and rate limiting steps of the kynurenine pathway as a key enzyme. To explore novel...