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Lois L Cavanagh

Explore the profile of Lois L Cavanagh including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 1762
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Recent Articles
1.
Zhu C, Boucheron N, Al-Rubaye O, Chung B, Thorbjornsen L, Kocher T, et al.
Gut . 2025 Mar; PMID: 40032499
Background: 24-Nor-ursodeoxycholic acid (NorUDCA) is a novel therapeutic bile acid for treating immune-mediated cholestatic liver diseases, such as primary sclerosing cholangitis (PSC). Objective: Since PSC strongly associates with T helper-type-like...
2.
Jain R, Tikoo S, On K, Martinez B, Dervish S, Cavanagh L, et al.
STAR Protoc . 2021 Aug; 2(3):100722. PMID: 34458865
Intravital multiphoton imaging of the tumor milieu allows for the dissection of intricate and dynamic biological processes . Herein, we present a step-by-step protocol for setting up an experimental cancer...
3.
Egawa G, Roediger B, Tay S, Cavanagh L, Guy T, Fazekas de B, et al.
Immunol Cell Biol . 2020 Oct; 99(3):299-308. PMID: 33002241
Staphylococcus aureus is one of the most common causes of community- and hospital-acquired bacterial infection worldwide. While neutrophils play an important role in anti-S. aureus immune defense, the role of...
4.
Obeidy P, Ju L, Oehlers S, Zulkhernain N, Lee Q, Galeano Nino J, et al.
Immunol Cell Biol . 2019 Nov; 98(2):93-113. PMID: 31698518
T lymphocytes utilize amoeboid migration to navigate effectively within complex microenvironments. The precise rearrangement of the actin cytoskeleton required for cellular forward propulsion is mediated by actin regulators, including the...
5.
Kinjyo I, Qin J, Tan S, Wellard C, Mrass P, Ritchie W, et al.
Nat Commun . 2015 Feb; 6:6301. PMID: 25709008
The precise pathways of memory T-cell differentiation are incompletely understood. Here we exploit transgenic mice expressing fluorescent cell cycle indicators to longitudinally track the division dynamics of individual CD8(+) T...
6.
Abtin A, Jain R, Mitchell A, Roediger B, Brzoska A, Tikoo S, et al.
Nat Immunol . 2013 Nov; 15(1):45-53. PMID: 24270515
Transendothelial migration of neutrophils in postcapillary venules is a key event in the inflammatory response against pathogens and tissue damage. The precise regulation of this process is incompletely understood. We...
7.
Pai S, Danne K, Qin J, Cavanagh L, Smith A, Hickey M, et al.
Front Cell Neurosci . 2013 Jan; 6:67. PMID: 23316136
Intravital imaging of the superficial brain tissue in mice represents a powerful tool for the dissection of the cellular and molecular cues underlying inflammatory and infectious central nervous system (CNS)...
8.
Tan S, Cavanagh L, dAdvigor W, Shackel N, Fazekas de St. Groth B, Weninger W
Immunol Cell Biol . 2012 Jan; 90(7):722-32. PMID: 22231652
Aging has profound effects on the immune system, including thymic involution, reduced diversity of the T cell receptor repertoire, reduced effector T cell and B cell function and chronic increase...
9.
Ng L, Qin J, Roediger B, Wang Y, Jain R, Cavanagh L, et al.
J Invest Dermatol . 2011 Jun; 131(10):2058-68. PMID: 21697893
Neutrophil granulocytes traffic into sites of organ injury in which they may not only participate in tissue repair and pathogen clearance but may also contribute to collateral cell damage through...
10.
Sumaria N, Roediger B, Ng L, Qin J, Pinto R, Cavanagh L, et al.
J Exp Med . 2011 Feb; 208(3):505-18. PMID: 21339323
The presence of γδ T cell receptor (TCR)-expressing cells in the epidermis of mice, termed dendritic epidermal T cells (DETCs), is well established. Because of their strict epidermal localization, it...