Loay Mahmoud
Overview
Explore the profile of Loay Mahmoud including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
22
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Recent Articles
1.
Cougnoux A, Mahmoud L, Johnsson P, Eroglu A, Gsell L, Rosenbauer J, et al.
Sci Rep
. 2025 Jan;
15(1):3811.
PMID: 39885179
Combining 3D cultures such as tumor spheroids and organoids with spatial omics holds great potential for tissue biology and cancer research. Yet, this potential is presently limited by technical and...
2.
Agarwal P, Glowacka A, Mahmoud L, Bazzar W, Larsson L, Alzrigat M
Int J Mol Sci
. 2023 May;
24(9).
PMID: 37175848
Amplification of the oncogene is found in ~20% of neuroblastoma (NB) cases and correlates with high-risk disease and poor prognosis. Despite the plethora of studies describing the role of MYCN...
3.
Mahmoud L, Cougnoux A, Bekiari C, Araceli Ruiz de Castroviejo Teba P, El Marrahi A, Panneau G, et al.
Exp Cell Res
. 2023 Mar;
425(2):113527.
PMID: 36889574
Breast cancer (BC) is the most commonly diagnosed cancer among women. Prognosis has improved over the years, to a large extent, owing to personalized therapy informed by molecular profiling of...
4.
Castell A, Yan Q, Fawkner K, Bazzar W, Zhang F, Wickstrom M, et al.
Cancer Res Commun
. 2023 Mar;
2(3):182-201.
PMID: 36874405
Significance: Our findings demonstrate that the small-molecule MYCMI-7 binds MYC and inhibits interaction between MYC and MAX, thereby hampering MYC-driven tumor cell growth in culture and while sparing normal cells.
5.
Masso-Valles D, Beaulieu M, Jauset T, Giuntini F, Zacarias-Fluck M, Foradada L, et al.
Cancer Res Commun
. 2023 Mar;
2(2):110-130.
PMID: 36860495
Significance: While MYC role in metastasis has been long controversial, this manuscript demonstrates that MYC inhibition by either transgenic expression or pharmacologic use of the recombinantly produced Omomyc miniprotein exerts...