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Llipsy Santiago

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Articles 28
Citations 409
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Recent Articles
1.
Chawla A, Vandereyken M, Arias M, Santiago L, Dikovskaya D, Nguyen C, et al.
Mucosal Immunol . 2024 Aug; 17(6):1242-1255. PMID: 39137883
Intestinal intraepithelial T lymphocytes (IEL) constitutively express high amounts of the cytotoxic proteases Granzymes (Gzm) A and B and are therefore thought to protect the intestinal epithelium against infection by...
2.
Senan-Salinas A, Comas L, Esteban P, Garzon-Tituana M, Cheng Z, Santiago L, et al.
ACS Pharmacol Transl Sci . 2024 May; 7(5):1474-1484. PMID: 38751645
Granzymes (Gzms), a family of serine proteases, expressed by immune and nonimmune cells, present perforin-dependent and independent intracellular and extracellular functions. When released in the extracellular space, GzmA, with trypsin-like...
3.
Ramirez-Labrada A, Santiago L, Pesini C, Arrieta M, Arias M, Calvo Perez A, et al.
Sci Rep . 2024 Feb; 14(1):4395. PMID: 38388659
Self-assembling peptides (SAPs) have gained significant attention in biomedicine because of their unique properties and ability to undergo molecular self-assembly driven by non-covalent interactions. By manipulating their composition and structure,...
4.
Giner J, Lebrero M, Trotta M, Rueda P, Vilalta L, Verde M, et al.
Vet Res Commun . 2023 Aug; 48(1):533-540. PMID: 37548874
SARS-CoV-2 is the causal agent of Coronavirus Disease 2019 (COVID-19) in humans that emerged in late 2019. This virus is able to infect humans and different animal species. Among pets,...
5.
Calvo J, Santiago L, Arias M, Pardo J, Albareda J, Martinez-Lostao L, et al.
Jt Dis Relat Surg . 2023 Jul; 34(2):271-278. PMID: 37462629
Objectives: This study aims to assess the development of osteoarthritis (OA) in granzyme A- (gzmA) and B- (gzmB) and perforin- (perf) knockout mice. Materials And Methods: A total of 75...
6.
Villanueva-Saz S, Martinez M, Rueda P, Bolea S, Perez M, Verde M, et al.
Vet Res Commun . 2023 Mar; 47(4):2179-2184. PMID: 36918467
Severe Acute Respiratory Syndrome Coronavirus 2 is the causative agent of Coronavirus Disease 2019 in humans. To date, little is known about the persistence of antibodies against SARS-CoV-2 in animals...
7.
Moreno-Martinez L, Santiago L, de la Torre M, Calvo A, Pardo J, Osta R
Int J Mol Sci . 2022 Nov; 23(21). PMID: 36362341
Granzyme A (gzmA), a serine protease involved in the modulation of the inflammatory immune response, is found at an elevated level in the serum from ALS patients. However, the influence...
8.
Villanueva-Saz S, Martinez M, Giner J, Gonzalez A, Tobajas A, Perez M, et al.
Vet Res Commun . 2022 Oct; 47(2):615-629. PMID: 36229725
Severe Acute Respiratory Syndrome Coronavirus 2 is the causative agent of Coronavirus Disease 2019 in humans. Among domestic animals, cats are more susceptible to SARS-CoV-2 than dogs. The detection of...
9.
Villanueva-Saz S, Giner J, Palomar A, Gomez M, Podra M, Del Carmen Aranda M, et al.
Animals (Basel) . 2022 Aug; 12(15). PMID: 35953960
The impact of the SARS-CoV-2 pandemic on wildlife is largely unevaluated, and extended surveillance of animal species is needed to reach a consensus on the role of animals in the...
10.
Pesini C, Hidalgo S, Arias M, Santiago L, Calvo C, Ocariz-Diez M, et al.
Oncoimmunology . 2022 Jul; 11(1):2096359. PMID: 35813574
The contribution of the T cell-related inhibitory checkpoint PD-1 to the regulation of NK cell activity is still not clear with contradictory results concerning its expression and role in the...