Iratxe Uranga-Murillo
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Explore the profile of Iratxe Uranga-Murillo including associated specialties, affiliations and a list of published articles.
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16
Citations
235
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Recent Articles
1.
Kelepouras K, Saggau J, Varanda A, Zrilic M, Kiefer C, Rakhsh-Khorshid H, et al.
Cell Death Differ
. 2024 May;
31(7):897-909.
PMID: 38783091
Necroptosis is a caspase-independent modality of cell death implicated in many inflammatory pathologies. The execution of this pathway requires the formation of a cytosolic platform that comprises RIPK1 and RIPK3...
2.
Albert M, Uranga-Murillo I, Arias M, de Miguel D, Pena N, Montinaro A, et al.
Cell Death Differ
. 2024 Mar;
31(5):544-557.
PMID: 38514848
The dysregulated immune response and inflammation resulting in severe COVID-19 are still incompletely understood. Having recently determined that aberrant death-ligand-induced cell death can cause lethal inflammation, we hypothesized that this...
3.
Moreo E, Jarit-Cabanillas A, Robles-Vera I, Uranga S, Guerrero C, Gomez A, et al.
Nat Commun
. 2023 Oct;
14(1):6090.
PMID: 37794033
Intravesical administration of Bacillus Calmette-Guérin (BCG) was one of the first FDA-approved immunotherapies and remains a standard treatment for bladder cancer. Previous studies have demonstrated that intravenous (IV) administration of...
4.
Martinez Lagunas K, Savcigil D, Zrilic M, Carvajal Fraile C, Craxton A, Self E, et al.
Sci Adv
. 2023 Jul;
9(30):eadg2829.
PMID: 37494451
Cell death coordinates repair programs following pathogen attack and tissue injury. However, aberrant cell death can interfere with such programs and cause organ failure. Cellular FLICE-like inhibitory protein (cFLIP) is...
5.
Baselga M, Moreo E, Uranga-Murillo I, Arias M, Junquera C
Histochem Cell Biol
. 2022 Sep;
159(1):47-60.
PMID: 36175690
The cytoskeleton not only deals with numerous interaction and communication mechanisms at the cellular level but also has a crucial role in the viral infection cycle. Although numerous aspects of...
6.
Baselga M, Uranga-Murillo I, de Miguel D, Arias M, Sebastian V, Pardo J, et al.
Materials (Basel)
. 2022 Jul;
15(14).
PMID: 35888208
The use of face masks and air purification systems has been key to curbing the transmission of SARS-CoV-2 aerosols in the context of the current COVID-19 pandemic. However, some masks...
7.
Lanuza P, Alonso M, Hidalgo S, Uranga-Murillo I, Garcia-Mulero S, Arnau R, et al.
Front Immunol
. 2022 Jun;
13:890836.
PMID: 35747143
Background: Colorectal cancer (CRC) is a heterogeneous disease with variable mutational profile and tumour microenvironment composition that influence tumour progression and response to treatment. While chemoresistant and poorly immunogenic CRC...
8.
Ramirez-Labrada A, Pesini C, Santiago L, Hidalgo S, Calvo-Perez A, Onate C, et al.
Front Immunol
. 2022 Jun;
13:896228.
PMID: 35651603
NK cells are key mediators of immune cell-mediated cytotoxicity toward infected and transformed cells, being one of the main executors of cell death in the immune system. NK cells recognize...
9.
Uranga-Murillo I, Morte E, Hidalgo S, Pesini C, Garcia-Mulero S, Sierra J, et al.
Theranostics
. 2022 Jan;
12(1):290-306.
PMID: 34987646
Coronavirus disease 2019 (COVID19), caused by SARS-CoV-2, is a complex disease, with a variety of clinical manifestations ranging from asymptomatic infection or mild cold-like symptoms to more severe cases requiring...
10.
Uranga-Murillo I, Tapia E, Garzon-Tituana M, Ramirez-Labrada A, Santiago L, Pesini C, et al.
Theranostics
. 2021 Nov;
11(20):9873-9883.
PMID: 34815792
Recent findings suggest that the serine protease Granzyme K (GzmK) may act as a proinflammatory mediator. However, its role in sepsis is unknown. Here we aim to understand the role...