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Liz Hernandez Borrero

Explore the profile of Liz Hernandez Borrero including associated specialties, affiliations and a list of published articles. Areas
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Citations 119
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Recent Articles
1.
Strandberg J, Louie A, Lee S, Hahn M, Srinivasan P, George A, et al.
J Clin Invest . 2025 Jan; 135(5). PMID: 39808500
Radiotherapy can be limited by pneumonitis, which is impacted by innate immunity, including pathways regulated by TRAIL death receptor DR5. We investigated whether DR5 agonists could rescue mice from toxic...
2.
Tajiknia V, Pinho-Schwermann M, Srinivasan P, Hernandez Borrero L, Zhang L, Huntington K, et al.
Am J Cancer Res . 2024 Oct; 14(9):4523-4536. PMID: 39417197
KRAS mutations occur in ~40-50% of mCRC and are associated with aggressive disease that is refractory to anti-EGFR therapies. Pancreatic cancer harbors ~90% KRAS driver gene mutation frequency. Small molecules...
3.
Zhang S, Carlsen L, Hernandez Borrero L, Seyhan A, Tian X, El-Deiry W
Biomolecules . 2022 Apr; 12(4). PMID: 35454137
is a tumor suppressor gene that encodes a sequence-specific DNA-binding transcription factor activated by stressful stimuli; it upregulates target genes involved in growth suppression, cell death, DNA repair, metabolism, among...
4.
Raufi A, Liguori N, Carlsen L, Parker C, Hernandez Borrero L, Zhang S, et al.
Front Pharmacol . 2021 Dec; 12:751568. PMID: 34916936
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease characterized by early metastasis, late detection, and poor prognosis. Progress towards effective therapy has been slow despite significant efforts. Novel treatment approaches...
5.
Tian X, Zhang S, Zhou L, Seyhan A, Hernandez Borrero L, Zhang Y, et al.
Front Pharmacol . 2021 Oct; 12:747837. PMID: 34630117
The integrated stress response (ISR) is an evolutionarily conserved intra-cellular signaling network which is activated in response to intrinsic and extrinsic stresses. Various stresses are sensed by four specialized kinases,...
6.
Hernandez Borrero L, Dicker D, Santiago J, Sanders J, Tian X, Ahsan N, et al.
Elife . 2021 Jul; 10. PMID: 34324416
Mutations in TP53 occur commonly in the majority of human tumors and confer aggressive tumor phenotypes, including metastasis and therapy resistance. CB002 and structural-analogs restore p53 signaling in tumors with...