Lisa Y Zhao
Overview
Explore the profile of Lisa Y Zhao including associated specialties, affiliations and a list of published articles.
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17
Citations
365
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Recent Articles
1.
Mahmud I, Tian G, Wang J, Hutchinson T, Kim B, Awasthee N, et al.
Nat Commun
. 2023 Apr;
14(1):1927.
PMID: 37045819
Cancer cells exhibit elevated lipid synthesis. In breast and other cancer types, genes involved in lipid production are highly upregulated, but the mechanisms that control their expression remain poorly understood....
2.
Xiao Y, Wang J, Zhao L, Chen X, Zheng G, Zhang X, et al.
Chem Commun (Camb)
. 2020 Aug;
56(68):9866-9869.
PMID: 32840532
Histone deacetylases (HDACs) are validated drug targets for cancer treatment. Increased HDAC isozyme selectivity and novel strategies to inhibit HDAC activity could lead to safer and more effective drug candidates....
3.
Li D, Tian G, Wang J, Zhao L, Co O, Underill Z, et al.
Prostate
. 2018 Jul;
78(15):1140-1156.
PMID: 30009471
Background: Mutations or truncation of the ligand-binding domain (LBD) of androgen receptor (AR) underlie treatment resistance for prostate cancer (PCa). Thus, targeting the AR N-terminal domain (NTD) could overcome such...
4.
Mikuls T, Walker C, Qiu F, Yu F, Thiele G, Alfant B, et al.
Rheumatology (Oxford)
. 2018 Mar;
57(7):1162-1172.
PMID: 29562298
Objectives: To profile and compare the subgingival microbiome of RA patients with OA controls. Methods: RA (n = 260) and OA (n = 296) patients underwent full-mouth examination and subgingival...
5.
Wang Y, Li D, Luo J, Tian G, Zhao L, Liao D
Sci Rep
. 2016 Nov;
6:37213.
PMID: 27849011
Cancer cells of epithelial and mesenchymal phenotypes exhibit different sensitivities to apoptosis stimuli, but the mechanisms underlying this phenomenon remain partly understood. We constructed a novel recombinant adenovirus expressing Ad12...
6.
Wang Y, Stowe R, Pinello C, Tian G, Madoux F, Li D, et al.
Chem Biol
. 2015 Feb;
22(2):273-84.
PMID: 25699604
Inhibitors of histone deacetylases (HDACi) hold considerable therapeutic promise as clinical anticancer therapies. However, currently known HDACi exhibit limited isoform specificity, off-target activity, and undesirable pharmaceutical properties. Thus, HDACi with...
7.
Santiago A, Li D, Zhao L, Godsey A, Liao D
Mol Biol Cell
. 2013 Jul;
24(17):2739-52.
PMID: 23825024
Chromosomal region maintenance 1 (CRM1) mediates p53 nuclear export. Although p53 SUMOylation promotes its nuclear export, the underlying mechanism is unclear. Here we show that tethering of a small, ubiquitin-like...
8.
Yang H, Pinello C, Luo J, Li D, Wang Y, Zhao L, et al.
Mol Cancer Ther
. 2013 Apr;
12(5):610-20.
PMID: 23625935
Acetyltransferase p300 (KAT3B) plays key roles in signaling cascades that support cancer cell survival and sustained proliferation. Thus, p300 represents a potential anticancer therapeutic target. To discover novel anticancer agents...
9.
Yang H, Zheng Z, Zhao L, Li Q, Liao D
Cell Cycle
. 2012 Jan;
11(3):582-93.
PMID: 22262167
Successful viral replication entails elimination or bypass of host antiviral mechanisms. Here, we show that shRNA-mediated knockdown of murine double minute (Mdm2) and its paralog Mdm4 enhanced the expression of...
10.
Li Q, Zhao L, Zheng Z, Yang H, Santiago A, Liao D
J Virol
. 2011 Jun;
85(16):7976-88.
PMID: 21680522
Adenovirus E1B-55K represses p53-mediated transcription. However, the phenotypic consequence of p53 inhibition by E1B-55K for cell cycle regulation and drug sensitivity in tumor cells has not been examined. In HCT116...