Lisa Wang
Overview
Explore the profile of Lisa Wang including associated specialties, affiliations and a list of published articles.
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158
Citations
3153
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Recent Articles
11.
Han R, Madariaga A, Gonzalez-Ochoa E, Smith A, Wang L, Lheureux S, et al.
Int J Gynecol Pathol
. 2024 Mar;
43(3):275-283.
PMID: 38436360
Mucinous ovarian carcinoma is an uncommon malignancy characterized by resistance to chemotherapy and poor survival in the metastatic setting. HER2 amplification is a frequent late event in carcinogenesis, yet the...
12.
Liu R, Wang L, Rizzo S, Garmhausen M, Pal N, Waliany S, et al.
Cell Rep Med
. 2024 Mar;
5(3):101444.
PMID: 38428426
Patients with cancer may be given treatments that are not officially approved (off-label) or recommended by guidelines (off-guideline). Here we present a data science framework to systematically characterize off-label and...
13.
Hernando-Calvo A, Malone E, Day D, Prawira A, Weinreb I, Yang S, et al.
Cancer Med
. 2023 Oct;
12(20):20299-20310.
PMID: 37818869
Objectives: We aimed to evaluate the activity of selinexor, an oral selective inhibitor of nuclear export, in patients with recurrent or metastatic salivary gland tumors (SGT). Methods: GEMS-001 is an...
14.
Gonzalez-Ochoa E, Milosevic M, Corr B, Abbruzzese J, Girda E, Miller R, et al.
Int J Gynecol Cancer
. 2023 Jun;
33(8):1208-1214.
PMID: 37380217
Objective: Wee1 kinase is a crucial regulator of the G2/M checkpoint which prevents entry of damaged DNA into mitosis. Adavosertib (AZD1775), a selective inhibitor of Wee1, induces G2 escape and...
15.
di Lazzaro Filho R, Yamamoto G, Silva T, Rocha L, Linnenkamp B, Castro M, et al.
J Med Genet
. 2023 Apr;
60(11):1127-1132.
PMID: 37055165
Rothmund-Thomson syndrome (RTS) is a rare, heterogeneous autosomal recessive genodermatosis, with poikiloderma as its hallmark. It is classified into two types: type I, with biallelic variants in and juvenile cataracts,...
16.
Madariaga A, Garg S, Tchrakian N, Dhani N, Jimenez W, Welch S, et al.
Nat Commun
. 2023 Mar;
14(1):1452.
PMID: 36922497
This multi-centre, non-randomized, open-label, phase II trial (NCT03016338), assessed niraparib monotherapy (cohort 1, C1), or niraparib and dostarlimab (cohort 2, C2) in patients with recurrent serous or endometrioid endometrial carcinoma....
17.
Marastoni S, Madariaga A, Pesic A, Nair S, Li Z, Shalev Z, et al.
Cancer Res Commun
. 2023 Mar;
2(5):293-306.
PMID: 36875717
Significance: The combination of the antifungal drug itraconazole with antimalarial drug hydroxychloroquine leads to a cytotoxic lysosomal dysfunction, supporting the rational for further research on lysosomal targeting in ovarian cancer.
18.
Chavez J, Foss F, William B, Brammer J, Smith S, Prica A, et al.
Clin Cancer Res
. 2023 Feb;
29(10):1869-1878.
PMID: 36826995
Purpose: Proliferation of T-follicular helper (TFH) CD4+ T cells is a postulated pathogenic mechanism for T-cell non-Hodgkin lymphomas (T-NHL). The inducible T-cell costimulator (ICOS) is highly expressed by TFH, representing...
19.
Aung K, McWhirter E, Welch S, Wang L, Lovell S, Stayner L, et al.
J Gastrointest Oncol
. 2023 Jan;
13(6):3216-3226.
PMID: 36636049
Background: Mitogen-activated protein kinase kinase (MEK) is activated by mutated KRAS in >90% of pancreatic ductal adenocarcinoma (PDAC). MEK and focal adhesion kinase (FAK) are frequently co-activated in PDAC providing...
20.
Johnson R, Qu X, Lin C, Huw L, Venkatanarayan A, Sokol E, et al.
Nat Commun
. 2022 Sep;
13(1):5478.
PMID: 36117191
Most colorectal (CRC) tumors are dependent on EGFR/KRAS/BRAF/MAPK signaling activation. ARID1A is an epigenetic regulator mutated in approximately 5% of non-hypermutated CRC tumors. Here we show that anti-EGFR but not...