Lisa Koole
Overview
Explore the profile of Lisa Koole including associated specialties, affiliations and a list of published articles.
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3
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3
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Recent Articles
1.
Leenders F, Koole L, Slaets H, Tiane A, van den Hove D, Vanmierlo T
Mech Ageing Dev
. 2024 Jul;
220:111959.
PMID: 38950628
Oligodendrocyte precursor cells (OPCs) comprise 5-8 % of the adult glial cell population and stand out as the most proliferative cell type in the central nervous system (CNS). OPCs are...
2.
Early Inhibition of Phosphodiesterase 4B (PDE4B) Instills Cognitive Resilience in APPswe/PS1dE9 Mice
Rombaut B, Schepers M, Tiane A, Mussen F, Koole L, Kessels S, et al.
Cells
. 2024 Jun;
13(12.
PMID: 38920631
Microglia activity can drive excessive synaptic loss during the prodromal phase of Alzheimer's disease (AD) and is associated with lowered cyclic adenosine monophosphate (cAMP) due to cAMP phosphodiesterase 4B (PDE4B)....
3.
Koole L, Martinez-Martinez P, van Amelsvoort T, Evelo C, Ehrhart F
World J Biol Psychiatry
. 2023 Nov;
25(2):116-129.
PMID: 37961844
Objectives: Schizophrenia is a psychiatric disorder affecting 1% of the population. Accumulating evidence indicates that neuroinflammation is involved in the pathology of these disorders by altering neurodevelopmental processes and specifically...