Lisa C Hudgins
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Explore the profile of Lisa C Hudgins including associated specialties, affiliations and a list of published articles.
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24
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752
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Recent Articles
1.
Gianos E, Duell P, Toth P, Moriarty P, Thompson G, Brinton E, et al.
Arterioscler Thromb Vasc Biol
. 2024 Oct;
44(12):e304-e321.
PMID: 39370995
Despite the availability of multiple classes of lipoprotein-lowering medications, some high-risk patients have persistent hypercholesterolemia and may require nonpharmacologic therapy. Lipoprotein apheresis (LA) is a valuable but underused adjunctive therapeutic...
2.
Reijman M, Tromp T, Hutten B, Hovingh G, Blom D, Catapano A, et al.
Lancet Child Adolesc Health
. 2024 May;
8(7):491-499.
PMID: 38759658
Background: Homozygous familial hypercholesterolaemia (HoFH) is a rare genetic disease characterised by extremely high plasma LDL cholesterol from birth, causing atherosclerotic cardiovascular disease at a young age. Lipoprotein apheresis in...
3.
Reijman M, Kusters D, Groothoff J, Arbeiter K, Dann E, de Boer L, et al.
Atherosclerosis
. 2024 Apr;
392:117525.
PMID: 38598969
Homozygous familial hypercholesterolaemia is a life-threatening genetic condition, which causes extremely elevated LDL-C levels and atherosclerotic cardiovascular disease very early in life. It is vital to start effective lipid-lowering treatment...
4.
Reijman M, Kusters D, Groothoff J, Arbeiter K, Dann E, de Boer L, et al.
medRxiv
. 2023 Nov;
PMID: 38014132
Homozygous familial hypercholesterolaemia is a life-threatening genetic condition, which causes extremely elevated LDL-C levels and atherosclerotic cardiovascular disease very early in life. It is vital to start effective lipid-lowering treatment...
5.
Cuchel M, Raal F, Hegele R, Al-Rasadi K, Arca M, Averna M, et al.
Eur Heart J
. 2023 May;
44(25):2277-2291.
PMID: 37130090
This 2023 statement updates clinical guidance for homozygous familial hypercholesterolaemia (HoFH), explains the genetic complexity, and provides pragmatic recommendations to address inequities in HoFH care worldwide. Key strengths include updated...
6.
Cuchel M, Lee P, Hudgins L, Duell P, Ahmad Z, Baum S, et al.
J Am Heart Assoc
. 2023 Apr;
12(9):e029175.
PMID: 37119068
Background Homozygous familial hypercholesterolemia (HoFH) is a rare, treatment-resistant disorder characterized by early-onset atherosclerotic and aortic valvular cardiovascular disease if left untreated. Contemporary information on HoFH in the United States...
7.
Omer L, Hudson E, Hudgins L, Boyd N
Stem Cells Dev
. 2021 May;
30(12):632-640.
PMID: 34029164
Homozygous familial hypercholesterolemia (hoFH) is a rare disorder caused primarily by pathological mutations in the low-density lipoprotein receptor (LDLR), which disrupts LDL-cholesterol (LDL-C) metabolism homeostasis. hoFH patients are at extremely...
8.
de Ferranti S, Shrader P, Linton M, Knowles J, Hudgins L, Benuck I, et al.
J Pediatr
. 2020 Sep;
229:70-77.
PMID: 32976895
Objective: To describe enrollment characteristics of youth in the Cascade Screening for Awareness and Detection of FH Registry. Study Design: This is a cross-sectional analysis of 493 participants aged <18 ...
9.
Miyashita K, Lutz J, Hudgins L, Toib D, Ashraf A, Song W, et al.
J Lipid Res
. 2020 Sep;
61(11):1365-1376.
PMID: 32948662
Some cases of chylomicronemia are caused by autoantibodies against glycosylphosphatidylinositol-anchored HDL binding protein 1 (GPIHBP1), an endothelial cell protein that shuttles LPL to the capillary lumen. GPIHBP1 autoantibodies prevent binding...
10.
Chyzhyk V, Kozmic S, Brown A, Hudgins L, Starc T, Davila A, et al.
J Clin Lipidol
. 2018 Oct;
13(1):89-99.
PMID: 30352774
Background: Triglyceride (TG) concentrations >2000 mg/dL are extremely elevated and increase the risk of pancreatitis. Objectives: We characterized five cases and two kindreds and ascertained prevalence in a reference laboratory...