Lisa A Brennan
Overview
Explore the profile of Lisa A Brennan including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
3550
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Costello M, Gilliland K, Mohamed A, Schey K, Johnsen S, Brennan L, et al.
PLoS One
. 2020 Nov;
15(11):e0241631.
PMID: 33180800
The unique cellular organization and transparent function of the ocular lens depend on the continuous differentiation of immature epithelial cells on the lens anterior surface into mature elongated fiber cells...
2.
Brennan L, McGreal-Estrada R, Logan C, Cvekl A, Menko A, Kantorow M
Exp Eye Res
. 2018 Jun;
174:173-184.
PMID: 29879393
The formation and life-long growth of the ocular lens depends on the continuous differentiation of lens epithelial cells into lens fiber cells. To achieve their mature structure and transparent function,...
3.
Costello M, Brennan L, Mohamed A, Gilliland K, Johnsen S, Kantorow M
PLoS One
. 2016 Aug;
11(8):e0160785.
PMID: 27536868
An unresolved issue in structural biology is how the encapsulated lens removes membranous organelles to carry out its role as a transparent optical element. In this ultrastructural study, we establish...
4.
He S, Limi S, McGreal R, Xie Q, Brennan L, Kantorow W, et al.
Development
. 2016 Jun;
143(11):1937-47.
PMID: 27246713
Ocular lens morphogenesis is a model for investigating mechanisms of cellular differentiation, spatial and temporal gene expression control, and chromatin regulation. Brg1 (Smarca4) and Snf2h (Smarca5) are catalytic subunits of...
5.
Klionsky D, Abdelmohsen K, Abe A, Abedin M, Abeliovich H, Arozena A, et al.
Autophagy
. 2016 Jan;
12(1):1-222.
PMID: 26799652
No abstract available.
6.
Chauss D, Brennan L, Bakina O, Kantorow M
J Biol Chem
. 2015 Nov;
290(51):30253-66.
PMID: 26527683
Accumulation of apoptotic material is toxic and associated with cataract and other disease states. Identification of mechanisms that prevent accumulation of apoptotic debris is important for establishing the etiology of...
7.
Chauss D, Basu S, Rajakaruna S, Ma Z, Gau V, Anastas S, et al.
G3 (Bethesda)
. 2014 Jun;
4(8):1515-27.
PMID: 24928582
The mature eye lens contains a surface layer of epithelial cells called the lens epithelium that requires a functional mitochondrial population to maintain the homeostasis and transparency of the entire...
8.
Costello M, Brennan L, Basu S, Chauss D, Mohamed A, Gilliland K, et al.
Exp Eye Res
. 2013 Sep;
116:141-50.
PMID: 24012988
The eye lens consists of a layer of epithelial cells that overlay a series of differentiating fiber cells that upon maturation lose their mitochondria, nuclei and other organelles. Lens transparency...
9.
McGreal R, Brennan L, Kantorow W, Wilcox J, Wei J, Chauss D, et al.
Exp Eye Res
. 2013 Mar;
110:10-7.
PMID: 23466869
αB-crystallin is a small heat shock protein that exhibits chaperone activity and can protect multiple cell types against oxidative stress damage. Altered levels and specific mutations of αB-crystallin are associated...
10.
McGreal R, Kantorow W, Chauss D, Wei J, Brennan L, Kantorow M
Biochim Biophys Acta
. 2012 Apr;
1820(7):921-30.
PMID: 22521365
Background: αB-crystallin/sHSP protects cells against oxidative stress damage. Here, we mechanistically examined its ability to preserve mitochondrial function in lens and retinal cells and protect cytochrome c under oxidative stress...