Lipi Thukral
Overview
Explore the profile of Lipi Thukral including associated specialties, affiliations and a list of published articles.
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Articles
40
Citations
2289
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Recent Articles
1.
Rathore S, Gahlot D, Castin J, Pandey A, Arvindekar S, Viswanath S, et al.
Biophys J
. 2024 Dec;
124(2):393-407.
PMID: 39674890
NOTCH, a single-pass transmembrane protein, plays a crucial role in cell fate determination through cell-to-cell communication. It interacts with two canonical ligands, Delta-like (DLL) and Jagged (JAG), located on neighboring...
2.
Das D, Sharma M, Gahlot D, Nia S, Gain C, Mecklenburg M, et al.
Mol Cell
. 2024 Nov;
84(22):4436-4453.e8.
PMID: 39520981
Lipophagy is a ubiquitous mechanism for degradation of lipid droplets (LDs) in lysosomes. Autophagy receptors selectively target organelles for lysosomal degradation. The selective receptor for lipophagy remains elusive. Using mouse...
3.
Neha , Castin J, Fatihi S, Gahlot D, Arun A, Thukral L
Database (Oxford)
. 2024 Sep;
2024.
PMID: 39298565
Autophagy pathway plays a central role in cellular degradation. The proteins involved in the core autophagy process are mostly localised on membranes or interact indirectly with lipid-associated proteins. Therefore, progress...
4.
Montero-Vergara J, Plachetta K, Kinch L, Bernhardt S, Kashyap K, Levine B, et al.
Cell Death Dis
. 2024 Jan;
15(1):14.
PMID: 38182563
GRB2 is an adaptor protein of HER2 (and several other tyrosine kinases), which we identified as a novel BECN1 (Beclin 1) interacting partner. GRB2 co-immunoprecipitated with BECN1 in several breast...
5.
Menon D, Bhapkar A, Manchandia B, Charak G, Rathore S, Jha R, et al.
Cell Rep
. 2023 Oct;
42(10):113203.
PMID: 37777960
Lipid droplets (LDs) play a crucial role in maintaining cellular lipid balance by storing and delivering lipids as needed. However, the intricate lipolytic pathways involved in LD turnover remain poorly...
6.
Malhotra N, Khatri S, Kumar A, Arun A, Daripa P, Fatihi S, et al.
Autophagy
. 2023 Jul;
19(12):3201-3220.
PMID: 37516933
AF2: AlphaFold2; AF2-Mult: AlphaFold2 multimer; ATG: autophagy-related; CTD: C-terminal domain; ECTD: extreme C-terminal domain; FR: flexible region; MD: molecular dynamics; NTD: N-terminal domain; pLDDT: predicted local distance difference test; UBL:...
7.
Zhang W, Nishimura T, Gahlot D, Saito C, Davis C, Jefferies H, et al.
Elife
. 2023 Jun;
12.
PMID: 37288820
Autophagy is an essential catabolic pathway which sequesters and engulfs cytosolic substrates via autophagosomes, unique double-membraned structures. ATG8 proteins are ubiquitin-like proteins recruited to autophagosome membranes by lipidation at the...
8.
Tooze S, Zhang W, Lazzeri G, Gahlot D, Thukral L, Covino R, et al.
FEBS Lett
. 2023 Jun;
598(1):107-113.
PMID: 37259601
Autophagy is a highly conserved intracellular pathway that is essential for survival in all eukaryotes. In healthy cells, autophagy is used to remove damaged intracellular components, which can be as...
9.
Paul S, Fatihi S, Sharma S, Kutum R, Fields R, Pant H, et al.
eNeuro
. 2022 Nov;
9(6).
PMID: 36351818
Hyperactivation of cyclin-dependent kinase 5 (Cdk5) by p25, contributes to neuroinflammation causing neurodegeneration in Parkinson's disease (PD) and Alzheimer's disease. However, the mechanism by which Cdk5 induces neuroinflammation in the...
10.
Subissi L, von Gottberg A, Thukral L, Worp N, Oude Munnink B, Rathore S, et al.
Nat Med
. 2022 May;
28(6):1110-1115.
PMID: 35637337
No abstract available.