Lionel Lim
Overview
Explore the profile of Lionel Lim including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
16
Citations
780
Followers
0
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Recent Articles
1.
Chong C, Jalali A, Wong H, Loft M, Wong R, Lee M, et al.
Asia Pac J Clin Oncol
. 2022 Jan;
18(5):e363-e368.
PMID: 35073441
Background: RAS mutation testing now routinely informs the optimal management of metastatic colorectal cancer (mCRC), specifically the finding of a RAS mutation defines patients who will not benefit from treatment...
2.
Anderton B, Camarda R, Balakrishnan S, Balakrishnan A, Kohnz R, Lim L, et al.
EMBO Rep
. 2017 Feb;
18(4):569-585.
PMID: 28219903
How MYC reprograms metabolism in primary tumors remains poorly understood. Using integrated gene expression and metabolite profiling, we identify six pathways that are coordinately deregulated in primary MYC-driven liver tumors:...
3.
Lee B, Wong H, Tacey M, Tie J, Wong R, Lee M, et al.
Asia Pac J Clin Oncol
. 2016 Nov;
13(4):314-321.
PMID: 27885818
Background: Debate continues regarding the benefits versus risks of initial resection of the primary tumor in metastatic colorectal cancer (mCRC) patients with an asymptomatic primary tumor. Although the benefit of...
4.
Nawaz H, Petraro P, Via C, Ullah S, Lim L, Wild D, et al.
Med Educ Online
. 2016 Aug;
21:29339.
PMID: 27507540
Background: The vast majority of the healthcare problems burdening our society today are caused by disease-promoting lifestyles (e.g., physical inactivity and unhealthy eating). Physicians report poor training and lack of...
5.
Wang S, Malik S, Tan I, Chan Y, Hoi Q, Ow J, et al.
J Mol Diagn
. 2016 Mar;
18(3):416-424.
PMID: 26970585
Targeted next-generation sequencing is becoming increasingly common as a clinical diagnostic and prognostic test for patient- and tumor-specific genetic profiles as well as to optimally select targeted therapies. Here, we...
6.
Wong H, Lee B, Field K, Lomax A, Tacey M, Shapiro J, et al.
Clin Colorectal Cancer
. 2016 Mar;
15(2):e9-e15.
PMID: 26968236
Background: With an ever-increasing focus on personalized medicine, all factors known to affect treatment response need to be considered when defining optimal therapy for individual patients. While the prognostic impact...
7.
Lim L, Balakrishnan A, Huskey N, Jones K, Jodari M, Ng R, et al.
Hepatology
. 2013 Aug;
59(1):202-15.
PMID: 23913442
Unlabelled: Hepatocellular carcinoma (HCC) is associated with poor survival for patients and few effective treatment options, raising the need for novel therapeutic strategies. MicroRNAs (miRNAs) play important roles in tumor...
8.
Mahmood S, Lim L, Akram Y, Alford-Morales S, Sherin K
Am J Prev Med
. 2013 Jun;
45(1):130-133.
PMID: 23790999
No abstract available.
9.
Koia J, Moyle R, Hendry C, Lim L, Botella J
Plant Mol Biol
. 2012 Dec;
81(4-5):327-36.
PMID: 23263857
The availability of a variety of promoter sequences is necessary for the genetic engineering of plants, in basic research studies and for the development of transgenic crops. In this study,...
10.
Upton J, Wang L, Han D, Wang E, Huskey N, Lim L, et al.
Science
. 2012 Oct;
338(6108):818-22.
PMID: 23042294
The endoplasmic reticulum (ER) is the primary organelle for folding and maturation of secretory and transmembrane proteins. Inability to meet protein-folding demand leads to "ER stress," and activates IRE1α, an...