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Linnea E Taniguchi

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Articles 8
Citations 78
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Recent Articles
1.
Sekulovski N, Wettstein J, Carleton A, Juga L, Taniguchi L, Ma X, et al.
Elife . 2024 Jul; 12. PMID: 39051990
Amniogenesis, a process critical for continuation of healthy pregnancy, is triggered in a collection of pluripotent epiblast cells as the human embryo implants. Previous studies have established that bone morphogenetic...
2.
Sekulovski N, Wettstein J, Carleton A, Juga L, Taniguchi L, Ma X, et al.
bioRxiv . 2024 Mar; PMID: 38496419
Amniogenesis, a process critical for continuation of healthy pregnancy, is triggered in a collection of pluripotent epiblast cells as the human embryo implants. Previous studies have established that BMP signaling...
3.
Wang S, Lin C, Carleton A, Cortez C, Johnson C, Taniguchi L, et al.
Sci Adv . 2021 Apr; 7(17). PMID: 33893097
Critical early steps in human embryonic development include polarization of the inner cell mass, followed by formation of an expanded lumen that will become the epiblast cavity. Recently described three-dimensional...
4.
Dougherty M, Lehman C, Spencer A, Mendez R, David A, Taniguchi L, et al.
Mol Cancer Res . 2020 May; 18(9):1392-1401. PMID: 32467173
EGFR inhibitors have shown poor efficacy in head and neck squamous cell carcinoma (HNSCC) with demonstrated involvement of the insulin-like growth factor-1 receptor (IGF1R) in resistance to EGFR inhibition. IGF1R...
5.
Lehman C, Khalil A, Axelrod M, Dougherty M, Schoeff S, Taniguchi L, et al.
Laryngoscope . 2019 Aug; 130(6):1470-1478. PMID: 31433065
Objectives: The insulin-like growth factor-1 receptor (IGF1R) has been implicated in therapeutic resistance in head and neck squamous cell carcinoma (HNSCC), and small molecule tyrosine kinase inhibitors (TKIs) of IGF1R...
6.
Lehman C, Mendez R, Dougherty M, Allak A, Adejumo O, Taniguchi L, et al.
Front Oncol . 2019 Feb; 9:13. PMID: 30729097
Epidermal growth factor receptor (EGFR) inhibitors have limited efficacy in head and neck squamous cell carcinoma (HNSCC) due to various resistance mechanisms, such as activation of the insulin-like growth factor-1...
7.
Jameson M, Taniguchi L, Vankoevering K, Stuart M, Francom C, Mendez R, et al.
J Oral Pathol Med . 2012 Oct; 42(4):332-8. PMID: 23106397
Background: Although oral squamous cell carcinomas (OSCCs) commonly overexpress the epidermal growth factor receptor (EGFR), EGFR tyrosine kinase inhibitors (TKIs) exhibit poor efficacy clinically. Activation of the insulin-like growth factor-1...
8.
Jameson M, Beckler A, Taniguchi L, Allak A, VanWagner L, Lee N, et al.
Mol Cancer Ther . 2011 Sep; 10(11):2124-34. PMID: 21878657
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) have poor efficacy in head and neck squamous carcinoma cells (HNSCC). Because the IGF-1 receptor (IGF1R) generates potent prosurvival signals and...