Lingchun Kong
Overview
Explore the profile of Lingchun Kong including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
578
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0
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Recent Articles
1.
Zheng Q, Weekley B, Vinson D, Zhao S, Bastle R, Thompson R, et al.
Nature
. 2025 Jan;
637(8047):974-982.
PMID: 39779849
Histone H3 monoaminylations at Gln5 represent an important family of epigenetic marks in brain that have critical roles in permissive gene expression. We previously demonstrated that serotonylation and dopaminylation of...
2.
Al-Kachak A, Di Salvo G, Fulton S, Chan J, Farrelly L, Lepack A, et al.
Nat Commun
. 2024 Jun;
15(1):5042.
PMID: 38871707
Mood disorders are an enigmatic class of debilitating illnesses that affect millions of individuals worldwide. While chronic stress clearly increases incidence levels of mood disorders, including major depressive disorder (MDD),...
3.
Al-Kachak A, Fulton S, Di Salvo G, Chan J, Farrelly L, Lepack A, et al.
bioRxiv
. 2023 May;
PMID: 37205414
Background: Major depressive disorder (MDD), along with related mood disorders, is a debilitating illness that affects millions of individuals worldwide. While chronic stress increases incidence levels of mood disorders, stress-mediated...
4.
Lukasak B, Mitchener M, Kong L, Dul B, Lazarus C, Ramakrishnan A, et al.
Proc Natl Acad Sci U S A
. 2022 Oct;
119(43):e2208672119.
PMID: 36256821
Recent studies have identified serotonylation of glutamine-5 on histone H3 (H3Q5ser) as a novel posttranslational modification (PTM) associated with active transcription. While H3Q5ser is known to be installed by tissue...
5.
Kong L, Li J, Yang Y, Tang H, Zou H
Bioengineered
. 2022 Jun;
13(5):13622-13631.
PMID: 35653799
Retinal vein occlusion (RVO) is a severe retinal vascular disease involving several complications, leading to weakening of vision and even blindness. Globally, over 16 million patients with RVO were found...
6.
Tang H, Kong L, Yang Y, Li J, Zou H
Bioengineered
. 2022 May;
13(5):11636-11645.
PMID: 35510332
The purpose of this study was to explore the mechanism by which puerarin regulated the expression of hypoxia-inducible factor 1α (HIF-1α) and vascular endothelial growth factor (VEGF) in humans' retinal...
7.
Reddy N, Majidi S, Kong L, Nemera M, Ferguson C, Moore M, et al.
Nat Commun
. 2021 Sep;
12(1):5702.
PMID: 34588434
Regulation of chromatin plays fundamental roles in the development of the brain. Haploinsufficiency of the chromatin remodeling enzyme CHD7 causes CHARGE syndrome, a genetic disorder that affects the development of...
8.
Wang Y, Kong L, Liu X
Int J Clin Exp Pathol
. 2020 Nov;
13(10):2447-2454.
PMID: 33165415
This study was designed to explore the effect of epidural block anesthesia combined with general anesthesia on postoperative cognitive ability of elderly patients undergoing thoracoscopic surgery. A total of 115...
9.
Goodman J, Yamada T, Yang Y, Kong L, Wu D, Zhao G, et al.
Nat Commun
. 2020 Jul;
11(1):3419.
PMID: 32647123
The development and function of the brain require tight control of gene expression. Genome architecture is thought to play a critical regulatory role in gene expression, but the mechanisms governing...
10.
Zhu L, Lv R, Kong L, Li X
Pregnancy Hypertens
. 2018 Dec;
14:59-67.
PMID: 30527120
Preeclampsia (PE) is a pregnancy-specific syndrome affecting up to 8% of pregnancies worldwide. While PE is a leading cause of maternal and neonatal mortality and morbidity, the pathophysiology of PE...