Lindsey J Organtini
Overview
Explore the profile of Lindsey J Organtini including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
233
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Recent Articles
1.
Goetschius D, Hartmann S, Organtini L, Callaway H, Huang K, Bator C, et al.
Proc Natl Acad Sci U S A
. 2021 Jun;
118(23).
PMID: 34074770
Canine parvovirus is an important pathogen causing severe diseases in dogs, including acute hemorrhagic enteritis, myocarditis, and cerebellar disease. Overlap on the surface of parvovirus capsids between the antigenic epitope...
2.
Subramanian S, Organtini L, Grossman A, Domeier P, Cifuente J, Makhov A, et al.
Virology
. 2017 Jul;
510:216-223.
PMID: 28750325
In minute virus of mice (MVM) capsids, icosahedral five-fold channels serve as portals mediating genome packaging, genome release, and the phased extrusion of viral peptides. Previous studies suggest that residues...
3.
Honey Bee Deformed Wing Virus Structures Reveal that Conformational Changes Accompany Genome Release
Organtini L, Shingler K, Ashley R, Capaldi E, Durrani K, Dryden K, et al.
J Virol
. 2016 Nov;
91(2).
PMID: 27852845
Importance: Honey bees are critical for global agriculture, but dramatic losses of entire hives have been reported in numerous countries since 2006. Deformed wing virus (DWV) and infestation with the...
4.
Lee H, Shingler K, Organtini L, Ashley R, Makhov A, Conway J, et al.
Sci Adv
. 2016 Aug;
2(8):e1501929.
PMID: 27574701
Many nonenveloped viruses engage host receptors that initiate capsid conformational changes necessary for genome release. Structural studies on the mechanisms of picornavirus entry have relied on in vitro approaches of...
5.
Shingler K, Organtini L, Hafenstein S
Bio Protoc
. 2016 Aug;
4(9).
PMID: 27547789
Since its discovery in 1969, enterovirus 71 (EV71) has emerged as a serious worldwide health threat. This member of the picornavirus family causes hand, foot, and mouth disease, and also...
6.
Organtini L, Lee H, Iketani S, Huang K, Ashley R, Makhov A, et al.
J Virol
. 2016 Aug;
90(21):9733-9742.
PMID: 27535057
Importance: Using cryo-electron microscopy and new direct electron detector technology, we have solved the 4 Å resolution structure of a Fab molecule bound to a picornavirus capsid. The Fab induced...
7.
Allison A, Organtini L, Zhang S, Hafenstein S, Holmes E, Parrish C
J Virol
. 2015 Oct;
90(2):753-67.
PMID: 26512077
Unlabelled: Sylvatic carnivores, such as raccoons, have recently been recognized as important hosts in the evolution of canine parvovirus (CPV), a pandemic pathogen of domestic dogs. Although viruses from raccoons...
8.
Organtini L, Allison A, Lukk T, Parrish C, Hafenstein S
J Virol
. 2014 Nov;
89(3):1909-12.
PMID: 25410876
Canine parvovirus type 2 (CPV-2) emerged in 1978 and spread worldwide within 2 years. Subsequently, CPV-2 was completely replaced by the variant CPV-2a, which is characterized by four specific capsid...
9.
Pan J, Zhang L, Organtini L, Hafenstein S, Bergelson J
J Virol
. 2014 Nov;
89(2):1324-8.
PMID: 25392210
Unlabelled: Many coxsackievirus B (CVB) isolates bind to human decay-accelerating factor (DAF) as well as to the coxsackievirus and adenovirus receptor (CAR). However, the virus does not interact with murine...
10.
Organtini L, Makhov A, Conway J, Hafenstein S, Carson S
J Virol
. 2014 Mar;
88(10):5755-65.
PMID: 24623425
Unlabelled: The coxsackievirus and adenovirus receptor (CAR) has been identified as the cellular receptor for group B coxsackieviruses, including serotype 3 (CVB3). CAR mediates infection by binding to CVB3 and...