Lindsay Festa
Overview
Explore the profile of Lindsay Festa including associated specialties, affiliations and a list of published articles.
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7
Citations
117
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Recent Articles
1.
Roth L, Zidane B, Festa L, Putatunda R, Romer M, Monnerie H, et al.
Glia
. 2020 Sep;
69(2):362-376.
PMID: 32894619
Regardless of adherence to combined antiretroviral therapy, white matter and myelin pathologies persist in patients with HIV-associated neurocognitive disorders, a spectrum of cognitive, motor, and behavioral impairments. We hypothesized that...
2.
Festa L, Roth L, Jensen B, Geiger J, Jordan-Sciutto K, Grinspan J
J Neuroimmune Pharmacol
. 2019 Nov;
16(1):169-180.
PMID: 31776836
Despite the introduction of antiretroviral (ARV) therapy (ART), approximately 30-50% of people living with human immunodeficiency virus-1 (HIV-1) will develop a spectrum of measurable neurocognitive dysfunction, collectively called HIV-associated neurocognitive...
3.
Nash B, Festa L, Lin C, Meucci O
Brain Res
. 2019 Aug;
1723:146409.
PMID: 31465771
Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) persist despite effective antiretroviral therapies (ART). Evidence suggests that modern HAND is driven by subtle synaptodendritic damage in select brain regions, as ART-treated...
4.
Nash B, Tarn K, Irollo E, Luchetta J, Festa L, Halcrow P, et al.
eNeuro
. 2019 Jul;
6(4).
PMID: 31300544
HIV-associated neurocognitive disorders (HAND) remain prevalent and are aggravated by µ-opioid use. We have previously shown that morphine and other µ-opioids may contribute to HAND by inhibiting the homeostatic and...
5.
Festa L, Gutoskey C, Graziano A, Waterhouse B, Meucci O
J Neurosci
. 2015 Jul;
35(29):10550-61.
PMID: 26203149
Synaptodendritic pruning and alterations in neurotransmission are the main underlying causes of HIV-associated neurocognitive disorders (HAND). Our studies in humans and nonhuman primates indicated that the protein ferritin heavy chain...
6.
Pitcher J, Abt A, Myers J, Han R, Snyder M, Graziano A, et al.
J Clin Invest
. 2014 Jan;
124(2):656-69.
PMID: 24401274
Interaction of the chemokine CXCL12 with its receptor CXCR4 promotes neuronal function and survival during embryonic development and throughout adulthood. Previous studies indicated that μ-opioid agonists specifically elevate neuronal levels...
7.
Festa L, Meucci O
Curr HIV Res
. 2012 May;
10(5):453-62.
PMID: 22591369
Human immunodeficiency virus 1 (HIV-1) and its associated proteins can have a profound impact on the central nervous system. Co-morbid abuse of opiates, such as morphine and heroin, is often...