Linda Leatherbury
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Explore the profile of Linda Leatherbury including associated specialties, affiliations and a list of published articles.
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28
Citations
1111
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Recent Articles
1.
Romanowicz J, Guerrelli D, Dhari Z, Mulvany C, Reilly M, Swift L, et al.
Am J Physiol Heart Circ Physiol
. 2021 Mar;
320(5):H1873-H1886.
PMID: 33739154
Compared with acyanotic congenital heart disease (CHD), cyanotic CHD has an increased risk of lifelong mortality and morbidity. These adverse outcomes may be attributed to delayed cardiomyocyte maturation, since the...
2.
Mokshagundam D, Kowalski W, Garcia-Pak I, Klaunberg B, Nam J, Mukouyama Y, et al.
Ultrasound Med Biol
. 2020 Dec;
47(3):751-758.
PMID: 33293111
In vivo micro-imaging of mice is useful in studying the genetic basis of cardiac development in mutant embryos. We examined Phox2b mutant mice, which lack autonomic innervation to the heart...
3.
Sugrue K, Sarkar A, Leatherbury L, Zohn I
Dis Model Mech
. 2018 Dec;
12(1).
PMID: 30578278
The development of the aortic arch is a complex process that involves remodeling of the bilaterally symmetrical pharyngeal arch arteries (PAAs) into the mature asymmetric aortic arch. Retinoic acid signaling...
4.
Liu X, Yagi H, Saeed S, Bais A, Gabriel G, Chen Z, et al.
Nat Genet
. 2017 May;
49(7):1152-1159.
PMID: 28530678
Congenital heart disease (CHD) affects up to 1% of live births. Although a genetic etiology is indicated by an increased recurrence risk, sporadic occurrence suggests that CHD genetics is complex....
5.
Leatherbury L, Berul C
Circ Cardiovasc Genet
. 2017 May;
10(3):e001746.
PMID: 28468791
No abstract available.
6.
Li Y, Yagi H, Onuoha E, Damerla R, Francis R, Furutani Y, et al.
PLoS Genet
. 2016 Feb;
12(2):e1005821.
PMID: 26918822
Heterotaxy, a birth defect involving left-right patterning defects, and primary ciliary dyskinesia (PCD), a sinopulmonary disease with dyskinetic/immotile cilia in the airway are seemingly disparate diseases. However, they have an...
7.
Sandeep N, Uchida Y, Ratnayaka K, McCarter R, Hanumanthaiah S, Bangoura A, et al.
J Thorac Cardiovasc Surg
. 2015 Nov;
151(4):1126-35.e2.
PMID: 26611747
Objectives: Patients with single ventricle congenital heart disease often form aortopulmonary collateral vessels via an unclear mechanism. To gain insights into the pathogenesis of aortopulmonary collateral vessels, we correlated angiogenic...
8.
Adams P, Tian X, Zahid M, Khalifa O, Leatherbury L, Lo C
Respir Med
. 2015 Aug;
109(9):1126-30.
PMID: 26233707
Introduction: Primary ciliary dyskinesia (PCD), a disease of impaired respiratory cilia motility, is often difficult to diagnose. Recent studies show low nasal nitric oxide (nNO) is closely linked to PCD,...
9.
Li Y, Klena N, Gabriel G, Liu X, Kim A, Lemke K, et al.
Nature
. 2015 Mar;
521(7553):520-4.
PMID: 25807483
Congenital heart disease (CHD) is the most prevalent birth defect, affecting nearly 1% of live births; the incidence of CHD is up to tenfold higher in human fetuses. A genetic...
10.
Garrod A, Zahid M, Tian X, Francis R, Khalifa O, Devine W, et al.
Ann Am Thorac Soc
. 2014 Oct;
11(9):1426-32.
PMID: 25302410
Rationale: Patients with congenital heart disease with heterotaxy exhibit a high prevalence of abnormal airway ciliary motion and low nasal nitric oxide, characteristics associated with primary ciliary dyskinesia, a reflection...