Linda H Shapiro
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Explore the profile of Linda H Shapiro including associated specialties, affiliations and a list of published articles.
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36
Citations
800
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Recent Articles
1.
Ghosh M, McGurk F, Norris R, Dong A, Nair S, Jellison E, et al.
J Immunol
. 2023 Dec;
212(4):663-676.
PMID: 38149920
Implanted medical devices, from artificial heart valves and arthroscopic joints to implantable sensors, often induce a foreign body response (FBR), a form of chronic inflammation resulting from the inflammatory reaction...
2.
Menon N, Goyal R, Lema C, Woods P, Tanguay A, Morin A, et al.
Exp Eye Res
. 2021 May;
208:108628.
PMID: 34048779
Dry eye disease (DED) affects hundreds of millions of people worldwide. It is characterized by the production of inflammatory cytokines and chemokines as well as damaging matrix metalloproteinases (MMPs) at...
3.
Ghosh M, Kelava T, Vrhovac Madunic I, Kalajzic I, Shapiro L
Sci Rep
. 2021 May;
11(1):10736.
PMID: 34031489
The transmembrane aminopeptidase CD13 is highly expressed in cells of the myeloid lineage, regulates dynamin-dependent receptor endocytosis and recycling and is a necessary component of actin cytoskeletal organization. Here, we...
4.
Devarakonda C, Meredith E, Ghosh M, Shapiro L
J Immunol
. 2020 Dec;
206(5):923-929.
PMID: 33380494
The Coronaviridae family includes the seven known human coronaviruses (CoV) that cause mild to moderate respiratory infections (HCoV-229E, HCoV-NL63, HCoV-OC43, HCoV-HKU1) as well as severe illness and death (MERS-CoV, SARS-CoV,...
5.
6.
Devarakonda C, Shearier E, Hu C, Grady J, Balsbaugh J, Makari J, et al.
J Pediatr Urol
. 2020 Jul;
16(4):466.e1-466.e9.
PMID: 32620509
Introduction And Objective: Reliable urinary biomarker proteins would be invaluable in identifying children with ureteropelvic junction obstruction (UPJO) as the existing biomarker proteins are inconsistent in their predictive ability. Therefore,...
7.
Ghosh M, Shapiro L
Mol Cell Oncol
. 2019 Nov;
6(6):e1648024.
PMID: 31692781
Membrane recycling is critical to numerous cell functions and its dysregulation contributes to cancer and metastasis. We established that activation of the transmembrane molecule aminopeptidase N (ANPEP, also known as...
8.
Devarakonda C, Pereira F, Smith J, Shapiro L, Ghosh M
Atherosclerosis
. 2019 Jun;
287:70-80.
PMID: 31229835
Background And Aims: Atherosclerosis is an inflammatory cardiovascular disorder characterized by accumulation of lipid-loaded macrophages in the intima. Prolonged accumulation leads to apoptosis of macrophages and eventually to progression of...
9.
Ghosh M, Lo R, Ivic I, Aguilera B, Qendro V, Devarakonda C, et al.
Sci Signal
. 2019 May;
12(579).
PMID: 31040262
Cell attachment to the extracellular matrix (ECM) requires a balance between integrin internalization and recycling to the surface that is mediated by numerous proteins, emphasizing the complexity of these processes....
10.
Dimitrova E, Caromile L, Laubenbacher R, Shapiro L
BMC Syst Biol
. 2018 Apr;
12(1):50.
PMID: 29631571
Background: Cell death as a result of ischemic injury triggers powerful mechanisms regulated by germline-encoded Pattern Recognition Receptors (PRRs) with shared specificity that recognize invading pathogens and endogenous ligands released...