Linda C Hassinger
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Explore the profile of Linda C Hassinger including associated specialties, affiliations and a list of published articles.
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4
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351
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Recent Articles
1.
Muschamp J, Hollander J, Thompson J, Voren G, Hassinger L, Onvani S, et al.
Proc Natl Acad Sci U S A
. 2014 Apr;
111(16):E1648-55.
PMID: 24706819
Hypocretin (orexin) and dynorphin are neuropeptides with opposing actions on motivated behavior. Orexin is implicated in states of arousal and reward, whereas dynorphin is implicated in depressive-like states. We show...
2.
Cataldo A, McPhie D, Lange N, Punzell S, Elmiligy S, Ye N, et al.
Am J Pathol
. 2010 Jun;
177(2):575-85.
PMID: 20566748
Postmortem, genetic, brain imaging, and peripheral cell studies all support decreased mitochondrial activity as a factor in the manifestation of Bipolar Disorder (BD). Because abnormal mitochondrial morphology is often linked...
3.
Cataldo A, Mathews P, Boiteau A, Hassinger L, Peterhoff C, Jiang Y, et al.
Am J Pathol
. 2008 Jun;
173(2):370-84.
PMID: 18535180
Endocytic dysfunction is an early pathological change in Alzheimer's disease (AD) and Down's syndrome (DS). Using primary fibroblasts from DS individuals, we explored the interactions among endocytic compartments that are...
4.
L-type calcium channels reduce ROS generation in cerebellar granule cells following kainate exposure
Leski M, Hassinger L, Valentine S, Baer J, Coyle J
Synapse
. 2001 Dec;
43(1):30-41.
PMID: 11746731
Cerebellar granule cells (CGC) deprived of serum or trophic factors develop sensitivity to kainate neurotoxicity that is mediated by the alpha-amino-3-hydroxy-5-methyl-isoxazole proprionic acid (AMPA) subtypes of glutamate receptors (GluR). The...