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Lin Z Li

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Articles 64
Citations 749
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Recent Articles
1.
Gupta P, Li L, Singh D, Nova S, Arias-Mendoza F, Orlovskiy S, et al.
Acad Radiol . 2025 Feb; PMID: 39984334
Rationale And Objectives: Melanoma, an aggressive skin cancer, often harbors BRAFV600E mutations driving tumor progression via the mitogen-activated protein kinase (MAPK) pathway. While targeted therapies like BRAF (dabrafenib) and MEK...
2.
Kollmar J, Xu J, Gonzalves D, Baur J, Li L, Tchou J, et al.
Cancers (Basel) . 2025 Jan; 17(1. PMID: 39796638
: Cancer cells rely on metabolic reprogramming that is supported by altered mitochondrial redox status and an increased demand for NAD. Over expression of Nampt, the rate-limiting enzyme of the...
3.
Podsednik A, Xu H, Li L
Transl Breast Cancer Res . 2024 Nov; 5:27. PMID: 39534579
Background: The redox status of nicotinamide adenine dinucleotide (NAD; including oxidized form NAD and reduced form NADH) plays key roles in both health and disease and has been actively studied...
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Xu H, Morrow R, Feng M, Zhao H, Wallace D, Li L
J Innov Opt Health Sci . 2024 Jul; 17(1). PMID: 39077370
Adenine nucleotide translocator (ANT) is a mitochondrial protein involved in the exchange of ADP and ATP across the mitochondrial inner membrane. It plays a crucial role in cellular energy metabolism...
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Xu H, Gonzalves D, Hoffman J, Baur J, Li L, Jensen E
Antioxidants (Basel) . 2024 May; 13(5). PMID: 38790651
Emerging data indicate that lung macrophages (LM) may provide a novel biomarker to classify disease endotypes in bronchopulmonary dysplasia (BPD), a form of infant chronic lung disease, and that augmentation...
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Peng A, Xu H, Moon L, Zhang P, Li L
Cancers (Basel) . 2024 May; 16(9). PMID: 38730620
To develop imaging biomarkers for tumors aggressiveness, our previous optical redox imaging (ORI) studies of the reduced nicotinamide adenine dinucleotide (NADH) and oxidized flavoproteins (Fp, containing flavin adenine dinucleotide, i.e.,...
8.
Ji X, Bao B, Li L, Pu J, Lin Y, Zhang X, et al.
Sci Data . 2024 Apr; 11(1):350. PMID: 38589476
Maintaining sufficient cerebral oxygen metabolism is crucial for human survival, especially in challenging conditions such as high-altitudes. Human cognitive neural activity is sensitive to fluctuations in oxygen levels. However, there...
9.
Arias-Mendoza F, Nath K, Xu H, Gupta P, Li L
Adv Exp Med Biol . 2022 Dec; 1395:323-328. PMID: 36527656
As a phosphorus-containing molecule, nicotinamide adenine dinucleotide is visible by phosphorus magnetic resonance spectroscopy (P-MRS). However, the relatively low cellular levels of its oxidised (NAD) and reduced (NADH) forms and...
10.
Xu H, Jacob A, Li L
Adv Exp Med Biol . 2022 Dec; 1395:269-274. PMID: 36527648
Co-enzyme nicotinamide adenine dinucleotide NAD(H) regulates hundreds of biochemical reactions within the cell. We previously reported that NAD(H) redox status may have prognostic value for predicting breast cancer metastasis. However,...