Lin-Yu Chen
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Explore the profile of Lin-Yu Chen including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
333
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Recent Articles
1.
Chen L, Chen H, Lai H, Lin S, Wen K, Darmawi , et al.
Taiwan J Obstet Gynecol
. 2025 Jan;
64(1):110-119.
PMID: 39794015
Objective: Endometrial cancer (EC) shows substantial heterogeneity in their immune microenvironment. BHLHE22 is consistently hypermethylated in EC and high expression of BHLHE22 is likely to be immunosuppressive in the tumor...
2.
Chen L, Chou Y, Liew P, Chu L, Wen K, Lin S, et al.
J Ovarian Res
. 2024 Dec;
17(1):243.
PMID: 39639363
No abstract available.
3.
Chen L, Yang S, Chou J, Chou H, Yeh C, Chiu C, et al.
Mol Carcinog
. 2024 Nov;
64(2):290-304.
PMID: 39540800
The role of TGF-β signaling in the epigenetic modifications involved in ovarian cancer is not fully understood. This study investigated the relationship between TGF-β signaling, epigenetic modifications, and cellular behaviors...
4.
Chen L, Chou Y, Liew P, Chu L, Wen K, Lin S, et al.
J Ovarian Res
. 2024 Oct;
17(1):194.
PMID: 39358778
Background: Ovarian cancer is the most lethal gynecological cancer. As the primary treatment, chemotherapy has a response rate of only 60-70% in advanced stages, and even lower as a second-line...
5.
Chen L, Shen Y, Chu L, Su P, Wang H, Weng Y, et al.
Antioxidants (Basel)
. 2024 Jun;
13(6).
PMID: 38929174
Ten-eleven translocation 1 (TET1) is a methylcytosine dioxygenase involved in active DNA demethylation. In our previous study, we demonstrated that TET1 reprogrammed the ovarian cancer epigenome, increased stem properties, and...
6.
Do Q, Su P, Chen C, Wang H, Lee Y, Weng Y, et al.
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982674
Window of implantation (WOI) genes have been comprehensively identified at the single cell level. DNA methylation changes in cervical secretions are associated with in vitro fertilization embryo transfer (IVF-ET) outcomes....
7.
Lee Y, Su P, Do A, Tzeng C, Hu Y, Chen C, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36675243
The causes of implantation failure remain a black box in reproductive medicine. The exact mechanism behind the regulation of endometrial receptivity is still unknown. Epigenetic modifications influence gene expression patterns...
8.
Liu W, Chen L, Huang Y, Fu L, Song L, Wang Y, et al.
Chin Herb Med
. 2022 Sep;
12(3):336-341.
PMID: 36119007
Objective: To make full usage of resource and turn waste into treasure, the chemical constituents and bioactivity were firstly investigated on Damask rose () flower residue (DRFR). Methods: DPPH and...
9.
Wen K, Huang R, Chen L, Wu T, Lu C, Chu T, et al.
Cancers (Basel)
. 2022 Sep;
14(17).
PMID: 36077877
Background: We describe a DNA methylation assay, named MPap test, using cervical scraping as an alternative technique for endometrial cancer detection. Methods: A multicenter hospital-based, two-stage validation study was conducted...
10.
Darmawi , Chen L, Su P, Liew P, Wang H, Weng Y, et al.
Int J Mol Sci
. 2022 Jul;
23(13).
PMID: 35806162
Endometrial cancer (EC) rates are rising annually. Additional prediction markers need to be evaluated because only 10-20% of EC cases show an objective response to immune-checkpoint inhibitors (ICIs). Our previous...