Lin-Lin Xu
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Explore the profile of Lin-Lin Xu including associated specialties, affiliations and a list of published articles.
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58
Citations
607
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Recent Articles
1.
Xu L, McIlroy S, Ni Y, Guibert I, Chen J, Rocha U, et al.
ISME Commun
. 2025 Feb;
5(1):ycae141.
PMID: 40008244
Microbial communities in marine sediments contribute significantly to the overall health and resiliency of marine ecosystems. However, increased human disturbance undermines biodiversity and, hence, natural functionality provided by marine sediments....
2.
Xu H, Ma Y, Xu L, Li Y, Liu Y, Li Y, et al.
Nat Commun
. 2025 Feb;
16(1):1413.
PMID: 39915470
Sample relatedness is a major confounder in genome-wide association studies (GWAS), potentially leading to inflated type I error rates if not appropriately controlled. A common strategy is to incorporate a...
3.
Yuan K, Zhuang H, Wei J, Shen Y, Yao H, Li M, et al.
Nat Commun
. 2025 Jan;
16(1):920.
PMID: 39843427
In drug development, the substitution of benzene rings in aniline-based drug candidates with saturated bridged bicyclic ring systems often enhances pharmacokinetic properties while preserving biological activity. However, current efforts predominantly...
4.
Li T, Xu L, Wu D, Liu J, Yang Y, Miao Z, et al.
J Org Chem
. 2025 Jan;
90(2):960-970.
PMID: 39746028
This study introduces a novel methodology for the direct construction of tetrasubstituted centers, utilizing secondary C(sp)-H and C(sp)-H substrates, specifically indolin-2-ones and indoles, through an innovative oxidative cross-coupling reaction. Facilitated...
5.
Shi S, Cui C, Xu L, Zhang J, Hao W, Wang J, et al.
Nat Commun
. 2024 Sep;
15(1):8474.
PMID: 39349925
Inherently chiral medium-ring derivatives have important applications in many research fields, such as materials science, molecular recognition, and asymmetric catalysis. However, the enantioselective assembly of these molecules, especially by organocatalytic...
6.
Facile access to -aryl/alkyl dithiocarbamates a three-component reaction under metal-free conditions
Xu L, Wang S, Sun J, Zhang R, Tong J, Xu D
Org Biomol Chem
. 2024 Sep;
22(37):7702-7706.
PMID: 39224970
The development of facile and convenient atom-economical methods for the preparation of organosulfur compounds from CS is a challenging endeavor. Herein, a one-pot, environmentally friendly method to access -aryl/alkyl dithiocarbamates...
7.
Chen Z, Xu L, Du W, Ouyang Y, Gu X, Fang Z, et al.
Clin Kidney J
. 2024 Aug;
17(8):sfae209.
PMID: 39145144
Background: This study investigates the link between genetic variants associated with kidney function and immunoglobulin A (IgA) nephropathy (IgAN) progression. Methods: We recruited 961 biopsy-proven IgAN patients and 651 non-IgAN...
8.
Xu L, Gan T, Li Y, Chen P, Shi S, Liu L, et al.
Kidney Dis (Basel)
. 2024 Jun;
10(3):167-180.
PMID: 38835407
Introduction: IgA nephropathy (IgAN) is a leading cause of end-stage renal disease. The exact pathogenesis of IgAN is not well defined, but some genetic studies have led to a novel...
9.
Gao M, Xu L, Li Y, Wang X, Chen P, Shi S, et al.
Kidney Int Rep
. 2024 May;
9(4):1057-1066.
PMID: 38765575
Introduction: Immunoglobulin A nephropathy (IgAN) has been reported to coexist with hepatitis B virus (HBV) infection. Despite the clinical significance of this association, there is a lack of comprehensive research...
10.
Tang C, Chen P, Xu L, Lv J, Shi S, Zhou X, et al.
J Am Soc Nephrol
. 2024 Apr;
35(8):1045-1057.
PMID: 38687828
No abstract available.