Liliane Tenenbaum
Overview
Explore the profile of Liliane Tenenbaum including associated specialties, affiliations and a list of published articles.
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35
Citations
806
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Recent Articles
1.
Fernandes-Pires G, Azevedo M, Lanzillo M, Roux-Petronelli C, Binz P, Cudalbu C, et al.
Mol Ther Methods Clin Dev
. 2024 May;
32(2):101251.
PMID: 38745894
Creatine deficiency syndromes (CDS), caused by mutations in (AGAT), , and , mainly affect the central nervous system (CNS). CDS show brain creatine (Cr) deficiency, intellectual disability with severe speech...
2.
Prymaczok N, De Francesco P, Mazzetti S, Humbert-Claude M, Tenenbaum L, Cappelletti G, et al.
NPJ Parkinsons Dis
. 2024 Jan;
10(1):10.
PMID: 38184623
Parkinson's disease is characterized by a progressive accumulation of alpha-Synuclein (αSyn) neuronal inclusions called Lewy bodies in the nervous system. Lewy bodies can arise from the cell-to-cell propagation of αSyn,...
3.
Azevedo M, Prince N, Humbert-Claude M, Mesa-Infante V, Jeanneret C, Golzne V, et al.
Mol Ther Methods Clin Dev
. 2023 Sep;
31:101106.
PMID: 37766790
Despite its established neuroprotective effect on dopaminergic neurons and encouraging phase I results, intraputaminal GDNF administration failed to demonstrate significant clinical benefits in Parkinson's disease patients. Different human GDNF doses...
4.
Tournier B, Bouteldja F, Amosse Q, Nicolaides A, Azevedo M, Tenenbaum L, et al.
ACS Omega
. 2023 Sep;
8(34):31225-31236.
PMID: 37663488
An increase in astrocyte reactivity has been described in Alzheimer's disease and seems to be related to the presence of a pro-inflammatory environment. Reactive astrocytes show an increase in the...
5.
6.
Azevedo M, Sander S, Jeanneret C, Olfat S, Tenenbaum L
J Neurosci Methods
. 2021 Mar;
354:109105.
PMID: 33652020
PV mice--> combined with AAV-FLEX vectors allowed efficient and specific targeting of PV interneurons in the striatum. However, diffusion of viral particles to the globus pallidus caused massive transduction of...
7.
Dwir D, Giangreco B, Xin L, Tenenbaum L, Cabungcal J, Steullet P, et al.
Mol Psychiatry
. 2020 Mar;
25(11):3105.
PMID: 32218526
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
8.
Azevedo M, Sander S, Tenenbaum L
J Clin Med
. 2020 Feb;
9(2).
PMID: 32046031
In a healthy adult brain, glial cell line-derived neurotrophic factor (GDNF) is exclusively expressed by neurons, and, in some instances, it has also been shown to derive from a single...
9.
Dwir D, Giangreco B, Xin L, Tenenbaum L, Cabungcal J, Steullet P, et al.
Mol Psychiatry
. 2019 Mar;
25(11):2889-2904.
PMID: 30911107
Various mechanisms involved in schizophrenia pathophysiology, such as dopamine dysregulation, glutamate/NMDA receptor dysfunction, neuroinflammation or redox imbalance, all appear to converge towards an oxidative stress "hub" affecting parvalbumine interneurones (PVI)...
10.
Lasbleiz C, Mestre-Frances N, Devau G, Luquin M, Tenenbaum L, Kremer E, et al.
Front Mol Neurosci
. 2019 Feb;
12:10.
PMID: 30804750
Parkinson's disease (PD) is a progressive CNS disorder that is primarily associated with impaired movement. PD develops over decades and is linked to the gradual loss of dopamine delivery to...