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Lihong Huo

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Articles 31
Citations 1103
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Recent Articles
11.
Liu S, Cadaneanu R, Zhang B, Huo L, Lai K, Li X, et al.
PLoS One . 2016 Oct; 11(10):e0163232. PMID: 27711225
Background: Benign human prostate tubule-initiating cells (TIC) and aggressive prostate cancer display common traits, including tolerance of low androgen levels, resistance to apoptosis, and microenvironment interactions that drive epithelial budding...
12.
Sun H, Yue P, Wang S, Huo L, Zhao Y, Xie S, et al.
Med Chem . 2016 May; 12(8):775-785. PMID: 27140183
Background: The development of antiangiogenic agents arises as a more effective and selective therapeutic approach for the treatment of cancer. In addition to reduced acute toxicity, the efficacy of chemotherapy...
13.
Liu H, Cadaneanu R, Lai K, Zhang B, Huo L, An D, et al.
Prostate . 2015 Feb; 75(7):764-76. PMID: 25663004
Background: Human fetal prostate buds appear in the 10th gestational week as solid cords, which branch and form lumens in response to androgen 1. Previous in vivo analysis of prostate...
14.
Wang D, Meng Q, Huo L, Yang M, Wang L, Chen X, et al.
Protein Cell . 2014 Dec; 6(2):152-6. PMID: 25482409
No abstract available.
15.
Liu M, Li D, Sun L, Chen J, Sun X, Zhang L, et al.
J Pathol . 2014 Feb; 233(2):138-47. PMID: 24488929
Tat, the transactivation factor of human immunodeficiency virus type 1 (HIV-1), represents one of the major players mediating the loss of CD4-positive T-lymphocytes in HIV-1-infected patients, primarily due to the...
16.
Ha S, Baver S, Huo L, Gata A, Hairston J, Huntoon N, et al.
PLoS One . 2013 Nov; 8(10):e77622. PMID: 24204898
Leptin acts via neuronal leptin receptors to control energy balance. Hypothalamic pro-opiomelanocortin (POMC) and agouti-related peptide (AgRP)/Neuropeptide Y (NPY)/GABA neurons produce anorexigenic and orexigenic neuropeptides and neurotransmitters, and express the...
17.
He M, Zhang L, Wang X, Huo L, Sun L, Feng C, et al.
PLoS One . 2013 Jul; 8(6):e67186. PMID: 23826228
The Tat protein of HIV-1 has several well-known properties, such as nucleocytoplasmic trafficking, transactivation of transcription, interaction with tubulin, regulation of mitotic progression, and induction of apoptosis. Previous studies have...
18.
Gamber K, Huo L, Ha S, Hairston J, Greeley S, Bjorbaek C
PLoS One . 2012 Jan; 7(1):e30485. PMID: 22276206
Diet-induced obesity (DIO) in rodents is characterized by impaired activation of signal-transducer and activator of transcription 3 (STAT3) by leptin receptors (LepRb) within the hypothalamic arcuate nucleus. This signaling defect...
19.
Li D, Xie S, Ren Y, Huo L, Gao J, Cui D, et al.
Protein Cell . 2011 Mar; 2(2):150-60. PMID: 21359602
Angiogenesis, a process by which the preexisting blood vasculature gives rise to new capillary vessels, is associated with a variety of physiologic and pathologic conditions. However, the molecular mechanism underlying...
20.
Huo L, Li D, Sun X, Shi X, Karna P, Yang W, et al.
J Biol Chem . 2011 Jan; 286(11):9280-6. PMID: 21220424
Reversible acetylation of Tat is critical for its transactivation activity toward HIV-1 transcription. However, the enzymes involved in the acetylation/deacetylation cycles have not been fully characterized. In this study, by...