Lieven Verhoye
Overview
Explore the profile of Lieven Verhoye including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
740
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Recent Articles
1.
Ssebyatika G, Dinkelborg K, Stroh L, Hinte F, Corneillie L, Hueffner L, et al.
Nat Commun
. 2025 Feb;
16(1):1995.
PMID: 40011441
Hepatitis E virus (HEV) causes 3.3 million symptomatic cases and 44,000 deaths per year. Chronic infections can arise in immunocompromised individuals, and pregnant women may suffer from fulminant disease as...
2.
Collignon L, Holmbeck K, Just A, Verhoye L, Velazquez-Moctezuma R, Fahnoe U, et al.
Hepatology
. 2024 Apr;
80(5):1227-1238.
PMID: 38652584
Background And Aims: HCV infection continues to be a major global health burden despite effective antiviral treatments. The urgent need for a protective vaccine is hindered by the scarcity of...
3.
Tran C, Kersten J, Yan J, Breinig M, Huth T, Poth T, et al.
Gastroenterology
. 2024 Apr;
167(3):522-537.
PMID: 38636680
Background & Aims: High expression of phosphatidylinositol 4-kinase III alpha (PI4KIIIα) correlates with poor survival rates in patients with hepatocellular carcinoma. In addition, hepatitis C virus (HCV) infections activate PI4KIIIα...
4.
Burm R, Van Houtte F, Verhoye L, Mesalam A, Ciesek S, Roingeard P, et al.
JHEP Rep
. 2023 Feb;
5(3):100646.
PMID: 36748051
Background & Aims: Elimination of chronic HBV/HDV infection remains a major global health challenge. Targeting excessive hepatitis B surface antigen (HBsAg) release may provide an interesting window of opportunity to...
5.
Burm R, Maravelia P, Ahlen G, Ciesek S, Caro Perez N, Pasetto A, et al.
Gut
. 2022 Aug;
72(6):1186-1195.
PMID: 35977815
Objective: Chronic HBV/HDV infections are a major cause of liver cancer. Current treatments can only rarely eliminate HBV and HDV. Our previously developed preS1-HDAg immunotherapy could induce neutralising antibodies to...
6.
Meister T, Bruggemann Y, Nocke M, Ulrich R, Schuhenn J, Sutter K, et al.
Proc Natl Acad Sci U S A
. 2022 Aug;
119(34):e2202653119.
PMID: 35969792
Hepatitis E virus (HEV) is the causative agent of hepatitis E in humans and is the leading cause of enterically transmitted viral hepatitis worldwide. Ribavirin (RBV) is currently the only...
7.
Viral Interference of Hepatitis C and E Virus Replication in Novel Experimental Co-Infection Systems
Burkard T, Proske N, Resner K, Collignon L, Knegendorf L, Friesland M, et al.
Cells
. 2022 Mar;
11(6).
PMID: 35326378
Background: Hepatitis C virus (HCV) constitutes a global health problem, while hepatitis E virus (HEV) is the major cause of acute viral hepatitis globally. HCV/HEV co-infections have been poorly characterized,...
8.
Collignon L, Verhoye L, Hakze-van der Honing R, van der Poel W, Meuleman P
Front Microbiol
. 2022 Mar;
13:819877.
PMID: 35295314
The hepatitis E virus (HEV) is responsible for 20 million infections worldwide per year. Although, HEV infection is mostly self-limiting, immunocompromised individuals may evolve toward chronicity. The lack of an...
9.
Desombere I, Van Houtte F, Farhoudi A, Verhoye L, Buysschaert C, Gijbels Y, et al.
Front Immunol
. 2022 Jan;
12:775098.
PMID: 34975862
Hepatitis C virus (HCV) is highly variable and transmits through infected blood to establish a chronic liver infection in the majority of patients. Our knowledge on the infectivity of clinical...
10.
Brown R, Tegtmeyer B, Sheldon J, Khera T, Anggakusuma , Todt D, et al.
Sci Adv
. 2020 Nov;
6(45).
PMID: 33148654
Hepatitis C virus (HCV) has no animal reservoir, infecting only humans. To investigate species barrier determinants limiting infection of rodents, murine liver complementary DNA library screening was performed, identifying transmembrane...