Lianhui Sun
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Explore the profile of Lianhui Sun including associated specialties, affiliations and a list of published articles.
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11
Citations
318
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Recent Articles
1.
He X, Wang Q, Cheng X, Wang W, Li Y, Nan Y, et al.
Cell
. 2025 Mar;
PMID: 40023152
Vitamin C (vitC) is essential for health and shows promise in treating diseases like cancer, yet its mechanisms remain elusive. Here, we report that vitC directly modifies lysine residues to...
2.
Zhong L, Xu D, He J, Sun L, Fan G, Zhu T, et al.
Int J Med Microbiol
. 2025 Feb;
318:151649.
PMID: 39965450
Objectives: phage therapy is a promising approach for infections caused by drug-resistant bacteria; this study evaluated the impact of pre-exposure to phage particles on subsequent therapy. Mice were exposed intradermally...
3.
Sun L, Fan G, Zhang Z, Chang D, Zhang X, Zhang T, et al.
Cell Rep
. 2025 Feb;
44(2):115269.
PMID: 39908142
Drug resistance significantly limits the efficacy of chemotherapy. The DNA mismatch repair (MMR) system maintains genomic stability by correcting DNA errors. During DNA-damaging treatments, cancer cells transiently increase their adaptive...
4.
Lactylated Apolipoprotein C-II Induces Immunotherapy Resistance by Promoting Extracellular Lipolysis
Chen J, Zhao D, Wang Y, Liu M, Zhang Y, Feng T, et al.
Adv Sci (Weinh)
. 2024 Jul;
11(38):e2406333.
PMID: 38981044
Mortality rates due to lung cancer are high worldwide. Although PD-1 and PD-L1 immune checkpoint inhibitors boost the survival of patients with non-small-cell lung cancer (NSCLC), resistance often arises. The...
5.
Sun L, Wang X, Chen L, Gao Z, Xu S, Hu C, et al.
Cell Insight
. 2023 Nov;
2(6):100127.
PMID: 37961047
Hypopharyngeal squamous cell carcinoma (HSCC) is a highly aggressive malignancy that constitutes approximately 95% of all hypopharyngeal carcinomas, and it carries a poor prognosis. The primary factor influencing the efficacy...
6.
Sun L, Zhang Y, Yang B, Sun S, Zhang P, Luo Z, et al.
Nat Commun
. 2023 Oct;
14(1):6523.
PMID: 37863889
Cuproptosis, caused by excessively high copper concentrations, is urgently exploited as a potential cancer therapeutic. However, the mechanisms underlying the initiation, propagation, and ultimate execution of cuproptosis in tumors remain...
7.
Fan G, Sun L, Meng L, Hu C, Wang X, Shi Z, et al.
Nat Commun
. 2021 Jan;
12(1):20.
PMID: 33397932
Drug resistance and tumor recurrence are major challenges in cancer treatment. Cancer cells often display centrosome amplification. To maintain survival, cancer cells achieve bipolar division by clustering supernumerary centrosomes. Targeting...
8.
Cheng J, He S, Wang M, Zhou L, Zhang Z, Feng X, et al.
Clin Cancer Res
. 2019 Mar;
25(12):3732-3743.
PMID: 30890550
Purpose: Tumor repopulation is known as a major cause of treatment failure and/or tumor recurrence after radiotherapy. The underlying mechanism remains unclear. Our previous study demonstrated that irradiated apoptotic cells...
9.
He S, Cheng J, Sun L, Wang Y, Wang C, Liu X, et al.
Cell Death Dis
. 2018 May;
9(6):648.
PMID: 29844348
Tumor repopulation during therapy is an important cause of treatment failure. Strategies to overcome repopulation are arising in parallel with advances in the comprehension of underlying biological mechanisms. Here, we...
10.
Shan P, Fan G, Sun L, Liu J, Wang W, Hu C, et al.
Curr Biol
. 2017 Aug;
27(15):2271-2284.e5.
PMID: 28756945
Most eukaryotic mRNAs are polyadenylated in the nucleus, and the poly(A)-tail is required for efficient mRNA export and translation. However, mechanisms governing mRNA transport remain unclear. Here, we report that...