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Liang Han

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Articles 471
Citations 7728
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Recent Articles
1.
Dai J, Lu X, Zhang C, Qu T, Li W, Su J, et al.
Mol Cancer . 2025 Mar; 24(1):79. PMID: 40089784
Background: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are remarkably effective for treating EGFR-mutant non-small cell lung cancer (NSCLC). However, patients inevitably develop acquired drug resistance, resulting in recurrence or...
2.
Min L, Yu W, Han L, Sun N, Zhang L, Liu X
Chem Biodivers . 2025 Mar; :e202500069. PMID: 40071638
Inspired by natural quinoline, a series of novel quinoline derivatives containing thioether groups were designed and synthesized. All target compounds were characterized using 1H NMR, 13C NMR, and HRMS. Their...
3.
Zhang W, Jiang H, Han L, Liu J, Wang J, He F, et al.
Nat Commun . 2025 Mar; 16(1):2300. PMID: 40055357
Fluorescent π-conjugated polymers (FCPs) are known for their superior brightness but are still unavailable for highly multiplexed molecular imaging in single cells as they are hydrophobic and lack targeting capability...
4.
Han L, Zhai W
Mol Med Rep . 2025 Feb; 31(4). PMID: 40017132
Ischemia‑reperfusion injury (IRI) refers to tissue or organ damage that occurs following a period of inadequate blood supply (ischemia) followed by restoration of blood flow (reperfusion) within a short time...
5.
Qu T, Zhang C, Lu X, Dai J, He X, Li W, et al.
Nat Commun . 2025 Feb; 16(1):1986. PMID: 40011431
As a well-known cancer risk region, the 8q24 locus is frequently amplified in a variety of solid tumors. Here we identify a pseudogene-derived oncogenic lncRNA, ZNF252P, which is upregulated in...
6.
Lang Y, Zhang Y, Xia H, Liu K, Fu Y, Han L, et al.
Adv Mater . 2025 Feb; :e2420096. PMID: 39988866
Blade coating is a promising tool for upscaling organic solar cells (OSCs). However, the performances of blade-coated OSCs still lag behind their spin-coated counterparts, limiting their competitive edge towards commercialization....
7.
Lv Z, Zeng Y, Lv T, Liu Q, Han L
Colloids Surf B Biointerfaces . 2025 Feb; 250:114585. PMID: 39983452
Parkinson's disease is a progressive neurodegenerative disorder, which is characterized by pathological changes and progressive loss of dopaminergic neurons in the substantia nigra, e.g., endoplasmic reticulum stress. The blood-brain barrier...
8.
Wei X, Ning G, Ma H, Yin Y, Ma J, Han L, et al.
Arch Biochem Biophys . 2025 Feb; 767:110349. PMID: 39978616
At the heart of cancer pathology lies the dysregulated cell cycle, which is often driven by aberrant activities of the cell cycle regulating, cyclin-dependent kinases (CDKs). Efforts to harness the...
9.
He Z, Ji Y, Yuan Y, Liang T, Liu C, Jiao Y, et al.
Front Pharmacol . 2025 Feb; 16:1532558. PMID: 39944625
Esophageal cancer (EC) presents substantial therapeutic challenges due to its high mortality rate and the tendency for diagnosis at advanced stages. Acknowledging the constraints of the existing current treatment paradigm,...
10.
Osuoji O, DeGrazia T, Rolader R, Cole E, Lawson K, Hilley H, et al.
JID Innov . 2025 Feb; 5(2):100329. PMID: 39944288
Bullous pemphigoid is a devastating autoimmune blistering disease with need for improved therapeutics. Limited data are available on the overall burden of pruritus and alterations over time; however, treatment of...