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Lianfu Deng

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Articles 175
Citations 3630
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Recent Articles
1.
Suo J, Gan Y, Xie Y, Xu S, Wang J, Chen D, et al.
Life Med . 2025 Jan; 2(6):lnad045. PMID: 39872060
The skeleton is an important structural and metabolic organ in human body, while aging is the physiological basis for degenerative skeletal diseases. China has the largest aging population in the...
2.
Shen Y, Li G, Wang J, Qi J, Cui W, Deng L
J Colloid Interface Sci . 2024 Oct; 679(Pt A):760-771. PMID: 39393153
The bionics of natural bone structures plays an essential role in the selection of materials for bone tissue engineering. Although the content of trace metallic elements in bone is low,...
3.
Xu Y, Chang L, Chen Y, Dan Z, Zhou L, Tang J, et al.
Adv Sci (Weinh) . 2024 Oct; 11(44):e2406428. PMID: 39377219
Age-related declines in self-renewal and multipotency of bone marrow mesenchymal stem cells (BMSCs) limit their applications in tissue engineering and clinical therapy. Thus, understanding the mechanisms behind BMSC senescence is...
4.
Du Y, Li C, Zhang Y, Xiong W, Wang F, Wang J, et al.
Research (Wash D C) . 2024 Sep; 2022:0003. PMID: 39290968
In situ-activated therapy is a decent option for localized diseases with improved efficacies and reduced side effects, which is heavily dependent on the local conversion or activation of bioinert components....
5.
Zheng J, Li X, Zhang F, Li C, Zhang X, Wang F, et al.
Adv Healthc Mater . 2024 Aug; 13(31):e2402117. PMID: 39155412
Balancing osteoblast-osteoclast (OB-OC) cross-talk is crucial for restoring bone tissue structure and function. Current clinical drugs targeting either osteogenesis or osteoclastogenesis fail to effectively regulate cross-talk, impeding efficient bone repair...
6.
Li X, Zhao J, Chen L, Zhou X, Qiu M, Deng L, et al.
Heliyon . 2024 Jul; 10(12):e32889. PMID: 39005918
Osteocytes are terminally differentiated cells derived from osteoblasts and are deeply embedded within the bone matrix. They play a critical role in bone remodeling by generating a lacuno-canalicular network (LCN)...
7.
Qiu M, Chang L, Tang G, Ye W, Xu Y, Tulufu N, et al.
Exp Mol Med . 2024 Jun; 56(7):1574-1590. PMID: 38945950
The hypoxia-inducible factor-1α (HIF-1α) pathway coordinates skeletal bone homeostasis and endocrine functions. Activation of the HIF-1α pathway increases glucose uptake by osteoblasts, which reduces blood glucose levels. However, it is...
8.
Lin F, Xiang L, Wu L, Liu Y, Jiang Q, Deng L, et al.
Sci Adv . 2024 Apr; 10(16):eadl3063. PMID: 38640234
The organelle network is a key factor in the repair and regeneration of lesion. However, effectively intervening in the organelle network which has complex interaction mechanisms is challenging. In this...
9.
Lin F, Wang Z, Xiang L, Wu L, Liu Y, Xi X, et al.
Adv Sci (Weinh) . 2024 Mar; 11(24):e2309934. PMID: 38477445
No abstract available.
10.
Zhang J, Jiang T, Zhang Y, Yang K, Zhao Y, Zhou Q, et al.
Phytother Res . 2024 Feb; 38(4):1863-1881. PMID: 38358766
Forsythia suspensa tea is a popular traditional Chinese medicine decoction for its healthy and therapeutic benefits. However, its effects in bone metabolism were not clear. In recent study, we uncovered...