Li Q Zhang
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Explore the profile of Li Q Zhang including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
178
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Recent Articles
1.
Strong A, Rao S, von Hardenberg S, Li D, Cox L, Lee P, et al.
Am J Med Genet A
. 2023 Feb;
191(5):1227-1239.
PMID: 36751037
AMOTL1 encodes angiomotin-like protein 1, an actin-binding protein that regulates cell polarity, adhesion, and migration. The role of AMOTL1 in human disease is equivocal. We report a large cohort of...
2.
Zhang L, Yang H, Yang S, Wang Y, Chen X, Lu H, et al.
Technol Cancer Res Treat
. 2019 Sep;
18:1533033819874773.
PMID: 31537175
Introduction: The mechanism of tumorigenesis and metastasis of ovarian cancer has not yet been elucidated. This study aimed to investigate the role and molecular mechanism of cytosolic nonspecific dipeptidase 2...
3.
Heruth D, Shortt K, Zhang N, Li D, Zhang L, Qing Ye S
J Pharmacol Exp Ther
. 2018 Aug;
367(1):95-100.
PMID: 30076262
Acetaminophen is commonly used to reduce pain and fever. Unfortunately, overdose of acetaminophen is a leading cause of acute liver injury and failure in many developed countries. The majority of...
4.
Zhang L, Nsumu M, Huang P, Heruth D, Riordan S, Shortt K, et al.
Am J Pathol
. 2018 Apr;
188(7):1640-1652.
PMID: 29684358
Acetaminophen overdose is the most common cause of acute liver injury (ALI) or acute liver failure in the United States. Its pathogenetic mechanisms are incompletely understood. Additional studies are warranted...
5.
Huang P, Lee Jr M, Sadrerafi K, Heruth D, Zhang L, Maulik D, et al.
Drug Des Devel Ther
. 2017 Apr;
11:629-641.
PMID: 28424540
Our previous study indicated that overexpression of nicotinamide phosphoribosyltransferase (NAMPT) aggravated acute lung injury, while knockdown of NAMPT expression attenuated ventilator-induced lung injury. Recently, we found that meta-carborane-butyl-3-(3-pyridinyl)-2E-propenamide (MC-PPEA, MC4),...
6.
Zhang L, van Haandel L, Xiong M, Huang P, Heruth D, Bi C, et al.
Cell Death Dis
. 2017 Mar;
8(3):e2705.
PMID: 28333140
Nicotinamide phosphoribosyltransferase (NAMPT) is a pleiotropic protein implicated in the pathogenesis of acute respiratory distress syndrome, aging, cancer, coronary heart diseases, diabetes, nonalcoholic fatty liver disease, obesity, rheumatoid arthritis, and...
7.
Riordan S, Heruth D, Zhang L, Qing Ye S
Cell Biosci
. 2015 Jul;
5:33.
PMID: 26137216
The Clustered Regions of Interspersed Palindromic Repeats-Cas9 (CRISPR/Cas9), a viral defense system found in bacteria and archaea, has emerged as a tour de force genome editing tool. The CRISPR/Cas9 system...
8.
Shortt K, Chaudhary S, Grigoryev D, Heruth D, Venkitachalam L, Zhang L, et al.
PLoS One
. 2014 Nov;
9(11):e111953.
PMID: 25372662
Acute respiratory distress syndrome (ARDS) is a lung condition characterized by impaired gas exchange with systemic release of inflammatory mediators, causing pulmonary inflammation, vascular leak and hypoxemia. Existing biomarkers have...
9.
Grigoryev D, Cheranova D, Heruth D, Huang P, Zhang L, Rabb H, et al.
BMC Nephrol
. 2013 Oct;
14:231.
PMID: 24152794
Background: Accumulated to-date microarray data on ischemia reperfusion injury (IRI) of kidney represent a powerful source for identifying new targets and mechanisms of kidney IRI. In this study, we conducted...
10.
Cheranova D, Gibson M, Kibiryeva N, Zhang L, Ye S
Genes Cells
. 2012 Apr;
17(5):420-30.
PMID: 22487217
This study profiled transcriptomes of human pulmonary microvascular endothelial cells (HMVEC-L) treated with pre-B-cell colony-enhancing factor (PBEF) siRNA or scrambled RNA to gain insight into transcriptional regulations of PBEF on...