Li-Ke Qu
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Explore the profile of Li-Ke Qu including associated specialties, affiliations and a list of published articles.
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15
Citations
399
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Recent Articles
1.
Chen S, Feng J, Zhao C, Yao L, Wang L, Meng L, et al.
Am J Cancer Res
. 2022 Dec;
12(11):4930-4953.
PMID: 36504899
Cancer is one of the main causes of death in humans worldwide, the development of more effective anticancer drugs that can inhibit the malignant progression of cancer cells is of...
2.
Chen S, Zhao C, Yao L, Wang L, Ma Y, Meng L, et al.
Acta Pharmacol Sin
. 2022 Jul;
44(1):189-200.
PMID: 35778489
The high incidence of lymphatic metastasis is closely related to poor prognosis and mortality in cancers. Potent inhibitors to prevent pathological lymphangiogenesis and lymphatic spread are urgently needed. The VEGF-C-VEGFR3...
3.
Min L, Ma R, Yuan H, Liu C, Dong B, Zhang C, et al.
Asian Pac J Cancer Prev
. 2015 Apr;
16(7):2819-26.
PMID: 25854368
Combinations of multiple biomarkers representing distinct aspects of metastasis may have better prognostic value for breast cancer patients, especially those in late stages. In this study, we evaluated the protein...
4.
Huang H, Han Y, Wu J, Tian Z, Qu L, Shou C
Beijing Da Xue Xue Bao Yi Xue Ban
. 2014 Apr;
46(2):183-9.
PMID: 24743803
Objective: To identify chemoresistance-associated secretory proteins by proteomic approaches, and to provide the basis for selecting suitable chemotherapy in gastric cancer treatment. Methods: Drug resistant cell lines were established by...
5.
HIWI expression profile in cancer cells and its prognostic value for patients with colorectal cancer
Zeng Y, Qu L, Meng L, Liu C, Dong B, Xing X, et al.
Chin Med J (Engl)
. 2011 Sep;
124(14):2144-9.
PMID: 21933617
Background: HIWI is a member of PIWI gene family and its expression is found in various tumors, indicating that it may play a pivotal role in tumor development. This study...
6.
Li W, Xing X, Qu L, Meng L, Shou C
Beijing Da Xue Xue Bao Yi Xue Ban
. 2009 Oct;
41(5):516-20.
PMID: 19829665
Objective: To construct PRL-3 gene C104S point mutation and CAAX deletion mutants: pcDNA3-myc-PRL-3 (C104S), pEGFP-PRL-3 (C104S), pcDNA3-myc-PRL-3 (DeltaCAAX) and pEGFP-PRL-3 (DeltaCAAX), and express these plasmids in eukaryotic cells. Methods: Recombinant...
7.
Baltzis D, Pluquet O, Papadakis A, Kazemi S, Qu L, Koromilas A
J Biol Chem
. 2007 Sep;
282(43):31675-87.
PMID: 17785458
Phosphorylation of eukaryotic initiation factor 2alpha (eIF2alpha) is mediated by a family of kinases that respond to various forms of environmental stress. The eIF2alpha kinases are critical for mRNA translation,...
8.
Su Q, Wang S, Baltzis D, Qu L, Raven J, Li S, et al.
EMBO Rep
. 2007 Feb;
8(3):265-70.
PMID: 17290288
The interferon (IFN)-inducible, double-stranded RNA activated protein kinase (PKR) is a dual-specificity kinase, which has an essential role in the regulation of protein synthesis by phosphorylating the translation eukaryotic initiation...
9.
Tang J, Qu L, Zhang J, Wang W, Michaelson J, Degenhardt Y, et al.
Nat Cell Biol
. 2006 Jul;
8(8):855-62.
PMID: 16845383
The tumour suppressor p53 induces apoptosis or cell-cycle arrest in response to genotoxic and other stresses. In unstressed cells, the anti-proliferative effects of p53 are restrained by mouse double minute...
10.
Su Q, Wang S, Baltzis D, Qu L, Wong A, Koromilas A
Proc Natl Acad Sci U S A
. 2005 Dec;
103(1):63-8.
PMID: 16373505
Phosphorylation of the alpha-subunit of translation eukaryotic initiation factor-2 (eIF2) leads to the inhibition of protein synthesis in response to diverse conditions of stress. Serine/threonine RNA-dependent protein kinase (PKR) is...