Li-Jin Hsu
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Explore the profile of Li-Jin Hsu including associated specialties, affiliations and a list of published articles.
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42
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1124
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Recent Articles
11.
Cheng Y, Chou Y, Lai F, Jan M, Chang T, Jou I, et al.
Acta Neuropathol Commun
. 2020 Feb;
8(1):6.
PMID: 32000863
Human WWOX gene resides in the chromosomal common fragile site FRA16D and encodes a tumor suppressor WW domain-containing oxidoreductase. Loss-of-function mutations in both alleles of WWOX gene lead to autosomal...
12.
Chou P, Lai F, Chen Y, Sie Y, Kuo H, Su W, et al.
Cell Death Discov
. 2019 May;
5:97.
PMID: 31123603
Proapoptotic tumor suppressor WWOX is upregulated in the early stage of cancer initiation, which probably provides limitation to cancer growth and progression. Later, WWOX protein is reduced to enhance cancer...
13.
Chen Y, Fang Y, Cheng Y, Lin C, Hsu L, Wang S, et al.
Sci Rep
. 2017 Jul;
7(1):5676.
PMID: 28720835
Annexin A2 (ANXA2), a phospholipid-binding protein, has multiple biological functions depending on its cellular localization. We previously demonstrated that IFN-γ-triggered ANXA2 secretion is associated with exosomal release. Here, we show...
14.
Hsu L, Chiang M, Sze C, Su W, Yap Y, Lee I, et al.
Front Cell Dev Biol
. 2016 Dec;
4:141.
PMID: 27999774
Hyaluronidase HYAL-2 is a membrane-anchored protein and also localizes, in part, in the lysosome. Recent study from animal models revealed that both HYAL-1 and HYAL-2 are essential for the metabolism...
15.
Chen Y, Fang Y, Chang C, Lin C, Hsu L, Wu S, et al.
J Mol Biol
. 2016 Nov;
429(1):142-157.
PMID: 27871932
During the process of autophagy, the autophagy-related proteins are translocated to autophagosome formation sites. Here, we demonstrate that S100A10 is required for ULK1 localization to autophagosome formation sites. Silencing of...
16.
Hsu L, Hong Q, Chen S, Kuo H, Schultz L, Heath J, et al.
Oncotarget
. 2016 Nov;
8(12):19137-19155.
PMID: 27845895
Malignant cancer cells frequently secrete significant amounts of transforming growth factor beta (TGF-β), hyaluronan (HA) and hyaluronidases to facilitate metastasizing to target organs. In a non-canonical signaling, TGF-β binds membrane...
17.
Chuang M, Chang J, Hsu L, Jan M, Lu F
Integr Cancer Ther
. 2016 Oct;
16(4):516-525.
PMID: 27698264
JC-001 is a Chinese medicine that has been used to treat liver disease; however, its significance in cancer treatment has not been characterized. In this study, we used an immunocompetent...
18.
Hong Q, Hsu L, Chou P, Chou Y, Lu C, Chen Y, et al.
Transl Respir Med
. 2016 May;
1(1):5.
PMID: 27234387
Recent studies have demonstrated that transforming growth factor beta (TGF-β1)-induced antiapoptotic factor (TIAF1) is able to form aggregates in the hippocampi of middle-aged normal individuals. The aggregating TIAF1 induces generation...
19.
Chen S, Lin P, Lin H, Huang S, Lai F, Sheu H, et al.
Oncotarget
. 2015 Mar;
6(10):8007-18.
PMID: 25779665
When COS7 fibroblasts and other cells were exposed to UVC irradiation and cold shock at 4°C for 5 min, rapid upregulation and nuclear accumulation of NOS2, p53, WWOX, and TRAF2...
20.
Lee M, Su W, Wang W, Lin S, Lu C, Chen Y, et al.
Oncotarget
. 2015 Feb;
6(6):3737-51.
PMID: 25686832
Zfra is a 31-amino-acid zinc finger-like protein, which participates in the tumor necrosis factor signaling. Here, we determined that when nude mice and BALB/c mice were pre-injected with nanogram levels...