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Lewis C Perrin

Explore the profile of Lewis C Perrin including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 239
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Recent Articles
1.
Samoylovich A, Jennings B, Shannon C, Coward J, Lourie R, Riordan J, et al.
Aust N Z J Obstet Gynaecol . 2023 Jun; 63(5):702-708. PMID: 37259677
Aims: To assess the safety and feasibility of hyperthermic intraperitoneal chemotherapy (HIPEC) during cytoreduction surgery (CRS) in advanced high-grade serous ovarian, fallopian tube and peritoneal cancer within an Australian context....
2.
Dutt M, Hartel G, Richards R, Shah A, Mohamed A, Apostolidou S, et al.
Proteomics Clin Appl . 2023 May; 17(4):e2200114. PMID: 37147936
Purpose: This study aimed to identify serum glycoprotein biomarkers for early detection of high-grade serous ovarian cancer (HGSOC), the most common and aggressive histotype of ovarian cancer. Experimental Design: The...
3.
He Y, Khan T, Kryza T, Jones M, Goh J, Lyons N, et al.
Mol Pharm . 2021 Aug; 18(9):3464-3474. PMID: 34448393
Optimal cytoreduction for ovarian cancer is often challenging because of aggressive tumor biology and advanced stage. It is a critical issue since the extent of residual disease after surgery is...
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Janda M, Robledo K, Gebski V, Armes J, Alizart M, Cummings M, et al.
Gynecol Oncol . 2021 Mar; 161(1):143-151. PMID: 33762086
Purpose: Intrauterine levonorgestrel (LNG-IUD) is used to treat patients with endometrial adenocarcinoma (EAC) and endometrial hyperplasia with atypia (EHA) but limited evidence is available on its effectiveness. The study determined...
6.
Khan T, He Y, Kryza T, Harrington B, Gunter J, Sullivan M, et al.
Cancers (Basel) . 2020 Apr; 12(4). PMID: 32260077
High stage and recurrent ovarian clear cell carcinoma (OCC) are associated with poor prognosis and resistance to chemotherapy. A distinguishing histological feature of OCC is abundant cytoplasmic stores of glucose,...
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Harrington B, He Y, Khan T, Puttick S, Conroy P, Kryza T, et al.
Theranostics . 2020 Feb; 10(5):2095-2114. PMID: 32104500
CUB-domain containing protein 1 (CDCP1) is a cancer associated cell surface protein that amplifies pro-tumorigenic signalling by other receptors including EGFR and HER2. Its potential as a cancer target is...
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Nguyen T, Carreira P, Sanchez-Luque F, Schauer S, Fagg A, Richardson S, et al.
Cell Rep . 2018 Jun; 23(13):3730-3740. PMID: 29949758
LINE-1 (L1) retrotransposons are a source of insertional mutagenesis in tumor cells. However, the clinical significance of L1 mobilization during tumorigenesis remains unclear. Here, we applied retrotransposon capture sequencing (RC-seq)...
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Sharma S, Zuniga F, Rice G, Perrin L, Hooper J, Salomon C
Oncotarget . 2017 Dec; 8(61):104687-104703. PMID: 29262670
Ovarian cancer usually has a poor prognosis because it predominantly presents as high stage disease. New approaches are required to develop more effective early detection strategies and real-time treatment response...
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Harrington B, He Y, Davies C, Wallace S, Adams M, Beaven E, et al.
Br J Cancer . 2016 Feb; 114(4):417-26. PMID: 26882065
Background: Development of targeted therapies for high-grade serous ovarian cancer (HGSC) remains challenging, as contributing molecular pathways are poorly defined or expressed heterogeneously. CUB-domain containing protein 1 (CDCP1) is a...