Lev P Ovchinnikov
Overview
Explore the profile of Lev P Ovchinnikov including associated specialties, affiliations and a list of published articles.
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34
Citations
1272
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Recent Articles
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Chernov K, Barbet A, Hamon L, Ovchinnikov L, Curmi P, Pastre D
J Biol Chem
. 2009 Oct;
284(52):36569-36580.
PMID: 19843517
Following exposure to various stresses (arsenite, UV, hyperthermia, and hypoxia), mRNAs are assembled into large cytoplasmic bodies known as "stress granules," in which mRNAs and associated proteins may be processed...
23.
Evdokimova V, Tognon C, Ng T, Ruzanov P, Melnyk N, Fink D, et al.
Cancer Cell
. 2009 May;
15(5):402-15.
PMID: 19411069
Increased expression of the transcription/translation regulatory protein Y-box binding protein-1 (YB-1) is associated with cancer aggressiveness, particularly in breast carcinoma. Here we establish that YB-1 levels are elevated in invasive...
24.
Svitkin Y, Evdokimova V, Brasey A, Pestova T, Fantus D, Yanagiya A, et al.
EMBO J
. 2008 Dec;
28(1):58-68.
PMID: 19078965
The interaction between the poly(A)-binding protein (PABP) and eukaryotic translational initiation factor 4G (eIF4G), which brings about circularization of the mRNA, stimulates translation. General RNA-binding proteins affect translation, but their...
25.
Chernov K, Mechulam A, Popova N, Pastre D, Nadezhdina E, Skabkina O, et al.
BMC Biochem
. 2008 Sep;
9:23.
PMID: 18793384
Background: YB-1 is a major regulator of gene expression in eukaryotic cells. In addition to its role in transcription, YB-1 plays a key role in translation and stabilization of mRNAs....
26.
Chernov K, Curmi P, Hamon L, Mechulam A, Ovchinnikov L, Pastre D
FEBS Lett
. 2008 Jul;
582(19):2875-81.
PMID: 18652827
A significant fraction of mRNAs is known to be associated in the form of mRNPs with microtubules for active transport. However, little is known about the interaction between mRNPs and...
27.
Evdokimova V, Ovchinnikov L, Sorensen P
Cell Cycle
. 2006 May;
5(11):1143-7.
PMID: 16721060
Current models of translational regulation are mostly focused on how translational factors engage a messenger mRNA to the ribosome to initiate translation. Since the majority of mRNAs in eukaryotes are...
28.
Evdokimova V, Ruzanov P, Anglesio M, Sorokin A, Ovchinnikov L, Buckley J, et al.
Mol Cell Biol
. 2005 Dec;
26(1):277-92.
PMID: 16354698
YB-1 is a broad-specificity RNA-binding protein that is involved in regulation of mRNA transcription, splicing, translation, and stability. In both germinal and somatic cells, YB-1 and related proteins are major...
29.
Sorokin A, Selyutina A, Skabkin M, Guryanov S, Nazimov I, Richard C, et al.
EMBO J
. 2005 Sep;
24(20):3602-12.
PMID: 16193061
YB-1 is a DNA/RNA-binding nucleocytoplasmic shuttling protein whose regulatory effect on many DNA- and RNA-dependent events is determined by its localization in the cell. Distribution of YB-1 between the nucleus...
30.
Skabkina O, Lyabin D, Skabkin M, Ovchinnikov L
Mol Cell Biol
. 2005 Mar;
25(8):3317-23.
PMID: 15798215
YB-1 is a member of the numerous families of proteins with an evolutionary ancient cold-shock domain. It is involved in many DNA- and RNA-dependent events and regulates gene expression at...