Leslie St Bernard
Overview
Explore the profile of Leslie St Bernard including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
129
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0
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Recent Articles
1.
St Bernard L, Abolade J, Mohri H, Markowitz M, Evering T
J Virol
. 2020 Aug;
94(20).
PMID: 32759323
HIV-1 evolution in the cerebrospinal fluid (CSF) and plasma may result in discordant drug resistance mutations (DRMs) in the compartments. Single-genome amplification (SGA) was used to generate partial HIV-1 polymerase...
2.
Markowitz M, Gettie A, St Bernard L, Andrews C, Mohri H, Horowitz A, et al.
J Infect Dis
. 2019 Jun;
221(9):1398-1406.
PMID: 31175822
Background: MK-8591 (4'-ethynyl-2-fluoro-2'-deoxyadenosine [EFdA]) is a novel reverse transcriptase-translocation inhibitor. Methods: We assessed MK-8591 as preexposure prophylaxis in the rhesus macaque model of intrarectal challenge with simian/human immunodeficiency virus (SHIV)....
3.
Andrews C, St Bernard L, Poon A, Mohri H, Gettie N, Spreen W, et al.
AIDS
. 2016 Dec;
31(4):461-467.
PMID: 27902508
Objective: We evaluated the effectiveness of cabotegravir (CAB; GSK1265744 or GSK744) long acting as preexposure prophylaxis (PrEP) against intravenous simian immunodeficiency virus (SIV) challenge in a model that mimics blood...
4.
Markowitz M, Deren S, Cleland C, La Mar M, Silva E, Batista P, et al.
J Infect Dis
. 2016 Aug;
214(9):1376-1382.
PMID: 27521361
Background: Chronic inflammation, as defined by persistent immune activation, is associated with adverse clinical outcomes. People who inject drugs (PWID) have evidence of persistent immune activation. Here, in a cohort...
5.
Andrews C, Yueh Y, Spreen W, St Bernard L, Boente-Carrera M, Rodriguez K, et al.
Sci Transl Med
. 2015 Jan;
7(270):270ra4.
PMID: 25589630
Long-acting GSK1265744 (GSK744 LA) is a strand transfer inhibitor of the HIV/SIV (simian immunodeficiency virus) integrase and was shown to be an effective preexposure prophylaxis (PrEP) agent in a low-dose...
6.
Evering T, Kamau E, St Bernard L, Farmer C, Kong X, Markowitz M
Retrovirology
. 2014 Aug;
11:65.
PMID: 25125210
Background: The widespread use of highly effective, combination antiretroviral therapy (cART) has led to a significant reduction in the incidence of HIV-associated dementia (HAD). Despite these advances, the prevalence of...