Leslie Naesens
Overview
Explore the profile of Leslie Naesens including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
284
Followers
0
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Recent Articles
1.
Messiaen A, Vandendriessche S, De Muynck E, Strubbe G, De Bus L, Schelstraete P, et al.
Eur J Clin Microbiol Infect Dis
. 2025 Jan;
PMID: 39862301
Purpose: Mortality and morbidity of patients with bloodstream infection (BSI) remain high despite advances in diagnostic methods and efforts to speed up reporting. This study investigated the impact of reporting...
2.
Mina E, Jackson K, Crawford A, Faulks M, Pathmanandavel K, Acquarola N, et al.
J Clin Immunol
. 2024 Feb;
44(3):66.
PMID: 38363477
B cells and their secreted antibodies are fundamental for host-defense against pathogens. The generation of high-affinity class switched antibodies results from both somatic hypermutation (SHM) of the immunoglobulin (Ig) variable...
3.
Kiselinova M, Naesens L, Huis In t Veld D, Boelens J, Van Braeckel E, Vande Weygaerde Y, et al.
Pathogens
. 2024 Jan;
13(1).
PMID: 38276158
Extrapulmonary nontuberculous mycobacterial (NTM) disease remains largely enigmatic, yet these mycobacteria are increasingly acknowledged as important opportunistic pathogens in humans. Traditionally, NTM infections have been identified across various anatomical locations,...
4.
Oyaert M, De Scheerder M, Van Herrewege S, Laureys G, Van Assche S, Cambron M, et al.
Eur J Clin Microbiol Infect Dis
. 2023 Nov;
43(1):177-185.
PMID: 37953413
We assessed the humoral and cellular immune responses after two booster mRNA vaccine administrations [BNT162b2 (Pfizer-BioNTech vaccine)] in cohorts of immunocompromised patients (n = 199) and healthy controls (HC) (n ...
5.
Exome Sequencing and Multigene Panel Testing in 1,411 Patients With Adult-Onset Neurologic Disorders
Schuermans N, Verdin H, Ghijsels J, Hellemans M, Debackere E, Bogaert E, et al.
Neurol Genet
. 2023 May;
9(3):e200071.
PMID: 37152446
Background And Objectives: Owing to their extensive clinical and molecular heterogeneity, hereditary neurologic diseases in adults are difficult to diagnose. The current knowledge about the diagnostic yield and clinical utility...
6.
Naesens L, Haerynck F, Gack M
Trends Immunol
. 2023 May;
44(6):435-449.
PMID: 37149405
Nucleic acid sensors survey subcellular compartments for atypical or mislocalized RNA or DNA, ultimately triggering innate immune responses. Retinoic acid-inducible gene-I (RIG-I) is part of the family of cytoplasmic RNA...
7.
Bosteels C, Van Damme K, De Leeuw E, Declercq J, Maes B, Bosteels V, et al.
Cell Rep Med
. 2022 Dec;
3(12):100833.
PMID: 36459994
GM-CSF promotes myelopoiesis and inflammation, and GM-CSF blockade is being evaluated as a treatment for COVID-19-associated hyperinflammation. Alveolar GM-CSF is, however, required for monocytes to differentiate into alveolar macrophages (AMs)...
8.
Naesens L, Muppala S, Acharya D, Nemegeer J, Bogaert D, Lee J, et al.
Sci Immunol
. 2022 Nov;
7(77):eabq4531.
PMID: 36399538
Herpes simplex virus 1 (HSV-1) infects several billion people worldwide and can cause life-threatening herpes simplex encephalitis (HSE) in some patients. Monogenic defects in components of the type I interferon...
9.
Schuermans N, Hemelsoet D, Terryn W, Steyaert S, Van Coster R, Coucke P, et al.
Orphanet J Rare Dis
. 2022 May;
17(1):210.
PMID: 35606766
Background: In order to facilitate the diagnostic process for adult patients suffering from a rare disease, the Undiagnosed Disease Program (UD-PrOZA) was founded in 2015 at the Ghent University Hospital...
10.
Dekeyser C, Naesens L, Offner F, De Vriendt C, Schauwvlieghe A, Kerre T, et al.
J Neuroimmunol
. 2022 Apr;
367:577866.
PMID: 35453041
A 49-year-old patient with a history of lymphoproliferation and autoimmune cytopenias presented with unexplained longitudinal extensive transverse myelitis. Flow cytometry on peripheral blood showed an elevated level of double negative...