Leslie E Rogler
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Explore the profile of Leslie E Rogler including associated specialties, affiliations and a list of published articles.
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14
Citations
464
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Recent Articles
1.
Peterson E, Polgar Z, Devakanmalai G, Li Y, Jaber F, Zhang W, et al.
Hepatol Commun
. 2019 Jan;
3(1):129-146.
PMID: 30620000
Hepatocyte transplantation is an attractive alternative to liver transplantation. Thus far, however, extensive liver repopulation by adult hepatocytes has required ongoing genetic, physical, or chemical injury to host liver. We...
2.
Rogler C, Matarlo J, Kosmyna B, Fulop D, Rogler L
Gene Expr
. 2016 Dec;
17(2):99-114.
PMID: 27938504
MicroRNAs (miRNAs) regulate cell fate selection and cellular differentiation. miRNAs of the miR23b polycistron (miR-23b, miR-27b, and miR-24) target components of the TGF-β signaling pathway and affect murine bile ductular...
3.
Rogler C, Bebawee R, Matarlo J, Locker J, Pattamanuch N, Gupta S, et al.
J Histochem Cytochem
. 2016 Nov;
65(1):33-46.
PMID: 27879410
Recent investigations have reported many markers associated with human liver stem/progenitor cells, "oval cells," and identified "niches" in diseased livers where stem cells occur. However, there has remained a need...
4.
Yovchev M, Jaber F, Lu Z, Patel S, Locker J, Rogler L, et al.
Sci Rep
. 2016 Jan;
6:19275.
PMID: 26763940
Liver repopulation by transplanted hepatocytes has not been achieved previously in a normal liver microenvironment. Here we report that adult rat hepatocytes transduced ex vivo with a lentivirus expressing a...
5.
Rogler L, Kosmyna B, Moskowitz D, Bebawee R, Rahimzadeh J, Kutchko K, et al.
Hum Mol Genet
. 2013 Sep;
23(2):368-82.
PMID: 24009312
Post-transcriptional processing of some long non-coding RNAs (lncRNAs) reveals that they are a source of miRNAs. We show that the 268-nt non-coding RNA component of mitochondrial RNA processing endoribonuclease, (RNase...
6.
Connolly E, Van Doorslaer K, Rogler L, Rogler C
Mol Cancer Res
. 2010 May;
8(5):691-700.
PMID: 20460403
Metastasis is a multistep process that involves the deregulation of oncogenes and tumor suppressors beyond changes required for primary tumor formation. RHOB is known to have tumor suppressor activity, and...
7.
Rogler C, LeVoci L, Ader T, Massimi A, Tchaikovskaya T, Norel R, et al.
Hepatology
. 2009 Jul;
50(2):575-84.
PMID: 19582816
Unlabelled: Transforming growth factor-beta / bone morphogenetic protein (TGFbeta/BMP) signaling has a gradient of effects on cell fate choice in the fetal mouse liver. The molecular mechanism to understand why...
8.
Connolly E, Melegari M, Landgraf P, Tchaikovskaya T, Tennant B, Slagle B, et al.
Am J Pathol
. 2008 Aug;
173(3):856-64.
PMID: 18688024
Alterations in microRNA (miRNA) expression in both human and animal models have been linked to many forms of cancer. Such miRNAs, which act directly as repressors of gene expression, have...
9.
Rogler C, Zhou H, LeVoci L, Rogler L
Hepatology
. 2007 Oct;
46(6):1971-8.
PMID: 17935221
Unlabelled: Recent studies have shown a pluripotential nature of stem cells that were previously thought to be committed to specific lineages. HBC-3 cells are a clonal fetal murine hepatoblast cell...
10.
Nierhoff D, LeVoci L, Schulte S, Goeser T, Rogler L, Shafritz D
Hepatology
. 2007 May;
46(2):535-47.
PMID: 17508344
Unlabelled: Isolation of hepatic stem cells from the adult liver (AL) has not yet been achieved due to the lack of specific cell surface markers. To identify new surface markers...