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Les Huson

Explore the profile of Les Huson including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 602
Followers 0
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Recent Articles
1.
Howard L, He J, Watson G, Huang L, Wharton J, Luo Q, et al.
Ann Am Thorac Soc . 2021 Mar; 18(6):981-988. PMID: 33735594
Iron deficiency, in the absence of anemia, is common in patients with idiopathic and heritable pulmonary arterial hypertension (PAH) and is associated with a worse clinical outcome. Oral iron absorption...
2.
Abbara A, Clarke S, Islam R, Prague J, Comninos A, Narayanaswamy S, et al.
Hum Reprod . 2017 Dec; 33(2):342-344. PMID: 29194495
No abstract available.
3.
Owen D, Fan J, Campioli E, Venugopal S, Midzak A, Daly E, et al.
Biochem J . 2017 Oct; 474(23):3985-3999. PMID: 29074640
The 18 kDa translocator protein (TSPO) is a ubiquitous conserved outer mitochondrial membrane protein implicated in numerous cell and tissue functions, including steroid hormone biosynthesis, respiration, cell proliferation, and apoptosis....
4.
Abbara A, Clarke S, Islam R, Prague J, Comninos A, Narayanaswamy S, et al.
Hum Reprod . 2017 Sep; 32(9):1915-1924. PMID: 28854728
Study Question: Can increasing the duration of LH-exposure with a second dose of kisspeptin-54 improve oocyte maturation in women at high risk of ovarian hyperstimulation syndrome (OHSS)? Summary Answer: A...
5.
Prague J, Roberts R, Comninos A, Clarke S, Jayasena C, Nash Z, et al.
Lancet . 2017 Apr; 389(10081):1809-1820. PMID: 28385352
Background: Hot flushes affect 70% of menopausal women and often severely impact physical, psychosocial, sexual, and overall wellbeing. Hormone replacement therapy is effective but is not without risk. Neurokinin B...
6.
Iyasere O, Brown E, Johansson L, Huson L, Smee J, Maxwell A, et al.
Clin J Am Soc Nephrol . 2015 Dec; 11(3):423-30. PMID: 26712808
Background And Objectives: In-center hemodialysis (HD) is often the default dialysis modality for older patients. Few centers use assisted peritoneal dialysis (PD), which enables treatment at home. This observational study...
7.
Rizzuto I, Stavraka C, Chatterjee J, Borley J, Hopkins T, Gabra H, et al.
Int J Gynecol Cancer . 2015 Feb; 25(3):416-22. PMID: 25647256
Objective: The aim of this study was to construct a prognostic index that predicts risk of relapse in women who have completed first-line treatment for ovarian cancer (OC). Methods: A...
8.
Libri V, Yandim C, Athanasopoulos S, Loyse N, Natisvili T, Law P, et al.
Lancet . 2014 May; 384(9942):504-13. PMID: 24794816
Background: Friedreich's ataxia is a progressive degenerative disorder caused by deficiency of the frataxin protein. Expanded GAA repeats within intron 1 of the frataxin (FXN) gene lead to its heterochromatinisation...
9.
Barnes G, Alam S, Carter G, Pedersen C, Lee K, Hubbard T, et al.
Circ Heart Fail . 2013 Mar; 6(3):482-91. PMID: 23519586
Background: To assess cardiovascular actions of APJ agonism during prolonged (Pyr(1))apelin-13 infusion and renin-angiotensin system activation. Methods And Results: Forty-eight volunteers and 12 patients with chronic stable heart failure attended...
10.
Rhodes C, Wharton J, Boon R, Roexe T, Tsang H, Wojciak-Stothard B, et al.
Am J Respir Crit Care Med . 2012 Dec; 187(3):294-302. PMID: 23220912
Rationale: MicroRNAs (miRNAs or miRs) are implicated in the pathogenesis of various cardiovascular diseases, including pulmonary arterial hypertension (PAH). Objectives: We sought to measure changes in plasma levels of miRNAs...