Leonhard Mullauer
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Explore the profile of Leonhard Mullauer including associated specialties, affiliations and a list of published articles.
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149
Citations
2634
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Recent Articles
1.
Mayr L, Neyazi S, Schwark K, Trissal M, Beck A, Labelle J, et al.
Cancer Cell
. 2025 Mar;
PMID: 40086436
PDGFRA is crucial to tumorigenesis and frequently genomically altered in high-grade glioma (HGG). In a comprehensive dataset of pediatric HGG (n = 261), we detect PDGFRA mutations and/or amplifications in...
2.
Mair T, Konig P, Mijovic M, Kalla J, Baskan A, Tran L, et al.
Mol Oncol
. 2025 Mar;
PMID: 40066744
Transforming growth factor beta (TGF-β) exhibits complex and context-dependent cellular responses. While it mostly induces tumor-suppressive effects in early stages of tumorigenesis, tumor-promoting properties are evident in advanced disease. This...
3.
Kleinberger M, Cifci D, Paiato C, Tomasich E, Mair M, Steindl A, et al.
Acta Neuropathol Commun
. 2025 Feb;
13(1):34.
PMID: 39972401
Background: Tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) have increasingly been reported to impact the brain metastatic process of solid tumors. However, data on intra-individual differences between primary tumor and...
4.
Haller F, Jimenez K, Baumgartner M, Lang M, Klotz A, Jambrich M, et al.
Cancer Prev Res (Phila)
. 2024 Apr;
17(7):311-324.
PMID: 38643981
Lynch syndrome (LS) is the most prevalent heritable form of colorectal cancer. Its early onset and high lifetime risk for colorectal cancer emphasize the necessity for effective chemoprevention. NFE2L2 (NRF2)...
5.
Oszwald A, Zisser L, Comperat E, Mullauer L
J Mol Diagn
. 2024 Mar;
26(5):423-429.
PMID: 38508412
Multigene next-generation sequencing (NGS) panels have become a routine diagnostic method in the contemporary practice of personalized medicine. To avoid inadequate test choice or interpretation, a detailed understanding of the...
6.
Pozzorini C, Andre G, Coletta T, Buisson A, Bieler J, Ferrer L, et al.
Cell Rep Med
. 2023 Dec;
4(12):101344.
PMID: 38118421
Homologous recombination deficiency (HRD) is a predictive biomarker for poly(ADP-ribose) polymerase 1 inhibitor (PARPi) sensitivity. Routine HRD testing relies on identifying BRCA mutations, but additional HRD-positive patients can be identified...
7.
Stepien N, Senfter D, Furtner J, Haberler C, Dorfer C, Czech T, et al.
Cancers (Basel)
. 2023 May;
15(9).
PMID: 37173990
Background: Liquid biopsy diagnostic methods are an emerging complementary tool to imaging and pathology techniques across various cancer types. However, there is still no established method for the detection of...
8.
Tomasich E, Steindl A, Paiato C, Hatziioannou T, Kleinberger M, Berchtold L, et al.
Clin Cancer Res
. 2023 Apr;
29(16):3225-3236.
PMID: 37036472
Purpose: HER3 belongs to a family of receptor tyrosine kinases with oncogenic properties and is targeted by a variety of novel anticancer agents. There is a huge unmet medical need...
9.
Madlener S, Furtner J, Stepien N, Senfter D, Mayr L, Zeyda M, et al.
Acta Neuropathol
. 2023 Apr;
145(6):843-846.
PMID: 37020088
No abstract available.
10.
Atanasova V, de Jesus Cardona C, Hejret V, Tiefenbacher A, Mair T, Tran L, et al.
Cell Mol Gastroenterol Hepatol
. 2023 Mar;
15(6):1391-1419.
PMID: 36868311
Background & Aims: Patient-derived organoid cancer models are generated from epithelial tumor cells and reflect tumor characteristics. However, they lack the complexity of the tumor microenvironment, which is a key...