Leonard Tan
Overview
Explore the profile of Leonard Tan including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
1903
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0
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Recent Articles
1.
Han X, Sui J, Nie K, Zhao Y, Lv X, Xie J, et al.
Leukemia
. 2024 Jul;
38(10):2276-2280.
PMID: 39080353
No abstract available.
2.
Dunsmore G, Guo W, Li Z, Bejarano D, Pai R, Yang K, et al.
Sci Immunol
. 2024 Jul;
9(97):eadk3981.
PMID: 39058763
Tumor-associated macrophages (TAMs) are a heterogeneous population of cells whose phenotypes and functions are shaped by factors that are incompletely understood. Herein, we asked when and where TAMs arise from...
3.
Ng M, Kwok I, Tan L, Shi C, Cerezo-Wallis D, Tan Y, et al.
Science
. 2024 Jan;
383(6679):eadf6493.
PMID: 38207030
Neutrophils are increasingly recognized as key players in the tumor immune response and are associated with poor clinical outcomes. Despite recent advances characterizing the diversity of neutrophil states in cancer,...
4.
Shin Park D, Kozaki T, Tiwari S, Moreira M, Khalilnezhad A, Torta F, et al.
Nature
. 2023 Nov;
623(7986):397-405.
PMID: 37914940
Microglia are specialized brain-resident macrophages that arise from primitive macrophages colonizing the embryonic brain. Microglia contribute to multiple aspects of brain development, but their precise roles in the early human...
5.
Tan L, Tan O, Sze C, Goh W
PLoS One
. 2023 Jan;
18(1):e0274299.
PMID: 36634041
Sentiment Analysis (SA) is a category of data mining techniques that extract latent representations of affective states within textual corpuses. This has wide ranging applications from online reviews to capturing...
6.
Teh Y, Chooi M, Liu D, Kwok I, Lai G, Ayub Ow Yong L, et al.
Sci Adv
. 2022 Mar;
8(9):eabj4641.
PMID: 35245124
Circulating Ly6C monocytes often undergo cellular death upon exhaustion of their antibacterial effector functions, which limits their capacity for subsequent macrophage differentiation. This shrouds the understanding on how the host...
7.
Cossarizza A, Chang H, Radbruch A, Abrignani S, Addo R, Akdis M, et al.
Eur J Immunol
. 2021 Dec;
51(12):2708-3145.
PMID: 34910301
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when performing flow cytometry experiments and includes comprehensive sections describing phenotypes and functional assays of all major...
8.
Shih C, Tan L, Li J, Tan Y, Cheng H, Ng L
Methods Mol Biol
. 2021 May;
2308:177-202.
PMID: 34057724
The complex bone marrow microenvironment or niche is an important anatomical structure responsible for hematopoiesis and providing support to the immune cells function. Being the source of immune and blood...
9.
Ng M, Tan L, Wang Q, Mackay C, Ng L
Sci China Life Sci
. 2021 Mar;
64(11):1829-1841.
PMID: 33661490
There is growing recognition that neutrophils play an important role in cancer initiation, progression and metastasis. Although they are typically characterized as short-lived effector cells, neutrophils have been shown to...
10.
Kwok I, Becht E, Xia Y, Ng M, Teh Y, Tan L, et al.
Immunity
. 2020 Jun;
53(2):303-318.e5.
PMID: 32579887
Granulocyte-monocyte progenitors (GMPs) have been previously defined for their potential to generate various myeloid progenies such as neutrophils and monocytes. Although studies have proposed lineage heterogeneity within GMPs, it is...