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Leo M Miyakoshi

Explore the profile of Leo M Miyakoshi including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 123
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Recent Articles
1.
Peron S, Miyakoshi L, Brill M, Manzano-Franco D, Serrano-Lopez J, Fan W, et al.
Stem Cell Reports . 2023 Nov; 18(12):2418-2433. PMID: 37995703
Although adult subependymal zone (SEZ) neural stem cells mostly generate GABAergic interneurons, a small progenitor population expresses the proneural gene Neurog2 and produces glutamatergic neurons. Here, we determined whether Neurog2...
2.
Miyakoshi L, Staeger F, Li Q, Pan C, Xie L, Kang H, et al.
Prog Neurobiol . 2023 Jul; 229:102512. PMID: 37482196
Earlier studies based on 2-photon imaging have shown that glymphatic cerebrospinal fluid (CSF) transport is regulated by the sleep-wake cycle. To examine this association, we used 3DISCO whole-body tissue clearing...
3.
Mathiesen B, Miyakoshi L, Cederroth C, Tserga E, Versteegh C, Bork P, et al.
Sci Transl Med . 2023 Jun; 15(702):eabq3916. PMID: 37379370
Inner ear gene therapy has recently effectively restored hearing in neonatal mice, but it is complicated in adulthood by the structural inaccessibility of the cochlea, which is embedded within the...
4.
Mollgard K, Beinlich F, Kusk P, Miyakoshi L, Delle C, Pla V, et al.
Science . 2023 Jan; 379(6627):84-88. PMID: 36603070
The central nervous system is lined by meninges, classically known as dura, arachnoid, and pia mater. We show the existence of a fourth meningeal layer that compartmentalizes the subarachnoid space...
5.
Riquelme-Sandoval A, de Sa-Ferreira C, Miyakoshi L, Hedin-Pereira C
Front Pharmacol . 2020 Dec; 11:596572. PMID: 33362550
Classically, the endocannabinoid system (ECS) consists of endogenous lipids, of which the best known are anandamide (AEA) and 2 arachidonoylglycerol (2-AG), their enzyme machinery for synthesis and degradation and their...
6.
Miyakoshi L, Marques-Coelho D, De Souza L, Lima F, Martins V, Zanata S, et al.
Front Cell Neurosci . 2017 Jun; 11:138. PMID: 28567003
In most mammalian brains, the subventricular zone (SVZ) is a germinative layer that maintains neurogenic activity throughout adulthood. Neuronal precursors arising from this region migrate through the rostral migratory stream...
7.
Sequerra E, Miyakoshi L, Froes M, Menezes J, Hedin-Pereira C
Cereb Cortex . 2010 Feb; 20(11):2583-91. PMID: 20154014
The mammalian subventricular zone (SVZ) contains progenitors derived from cerebral cortex radial glia cells, which give rise to glutamatergic pyramidal neurons during embryogenesis. However, during postnatal life, SVZ generates neurons...